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Survivin 抗体 (C-Term)

This anti-Survivin antibody is a 兔 多克隆 antibody detecting Survivin in WB, ELISA 和 IHC (p). Suitable for 小鼠.
产品编号 ABIN6990324
发货至: 中国

Quick Overview for Survivin 抗体 (C-Term) (ABIN6990324)

抗原

See all Survivin (BIRC5) 抗体
Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This Survivin antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    纯化方法

    Survivin Antibody is affinity chromatography purified via peptide column.

    免疫原

    Survivin antibody was raised against a synthetic peptide corresponding to amino acids near the carboxy terminus of mouse Survivin. The immunogen is located within the last 50 amino acids of Survivin.

    亚型

    IgG
  • 应用备注

    mSurvivin antibody can be used for detection of survivin by Western blot at 1 μ,g/mL. An approximate 17 kDa band can be detected. Antibody can also be used for immunohistochemistry starting at 10 μ,g/mL.

    Antibody validated: Western Blot in mouse samples and Immunohistochemistry in mouse samples. All other applications and species not yet tested.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Survivin Antibody is supplied in PBS containing 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C,4 °C

    储存方法

    mSurvivin antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原

    Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

    别名

    Survivin

    背景

    Survivin Antibody: Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP. Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas.

    分子量

    17 kDa

    基因ID

    332

    NCBI登录号

    NP_001159

    UniProt

    O15392

    途径

    Apoptosis, Cell Division Cycle, Nuclear Hormone Receptor Binding
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