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SARS-CoV-2 Spike 抗体

适用: SARS Coronavirus-2 (SARS-CoV-2) ELISA 宿主: Human Monoclonal 5E8 unconjugated
产品编号 ABIN6990096
发货至: 中国
  • 抗原 See all SARS-CoV-2 Spike 抗体
    SARS-CoV-2 Spike
    适用
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    SARS Coronavirus-2 (SARS-CoV-2)
    宿主
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    Human
    克隆类型
    • 42
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    单克隆
    标记
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    This SARS-CoV-2 Spike antibody is un-conjugated
    应用范围
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    ELISA
    特异性
    Antibody recognizes 2019-nCoV S-RBD Protein.
    纯度
    95,00%
    免疫原
    Cultured in vitro under conditions free from animal derived components.
    克隆位点
    5E8
    亚型
    IgG1
    Top Product
    Discover our top product SARS-CoV-2 Spike Primary Antibody
  • 应用备注
    Immunoreactivity: 80-120 % compared to the reference sample in an ELISA test.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    5.0 mg/mL
    缓冲液
    PBS, pH 7.4
    储存条件
    -20 °C,4 °C
    储存方法
    24 months from manufacturing at <-20 °C, 1 month, 2 to 8 °C under sterile conditions.
  • 抗原
    SARS-CoV-2 Spike
    Abstract
    SARS-CoV-2 Spike 产品
    别名
    E2 antibody, E2 glycoprotein precursor antibody, Surface Glycoprotein antibody, S antibody
    物质类
    Viral Protein
    背景
    The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
    基因ID
    43740568
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