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CEND1 抗体

CEND1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p), IF (cc) 宿主: 兔 Monoclonal 1D12 unconjugated
产品编号 ABIN6989616
发货至: 中国
  • 抗原 See all CEND1 抗体
    CEND1 (Cell Cycle Exit and Neuronal Differentiation 1 (CEND1))
    适用
    • 14
    • 11
    • 11
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 14
    • 1
    克隆类型
    • 13
    • 2
    单克隆
    标记
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CEND1 antibody is un-conjugated
    应用范围
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Synthetic Peptide within N-terminal Human CEND1.
    克隆位点
    1D12
    亚型
    IgG
    Top Product
    Discover our top product CEND1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    CEND1 (Cell Cycle Exit and Neuronal Differentiation 1 (CEND1))
    别名
    CEND1 (CEND1 产品)
    别名
    BM88 antibody, 1500001H12Rik antibody, AI415214 antibody, C38 antibody, RGD1309401 antibody, cell cycle exit and neuronal differentiation 1 antibody, CEND1 antibody, Cend1 antibody
    背景

    Synonyms: BM88 antibody, BM88 antigen antibody, Cell cycle exit and neuronal differentiation 1 antibody, Cell cycle exit and neuronal differentiation protein 1 antibody, FLJ90066 antibody, MGC34326 antibody

    Background: BM88 is a 149 amino acid protein that belongs to the CEND1 familly. Involved in neuroblastoma cell differentiation, BM88 is a single-pass type IV membrane protein that is neuron specific. It is suggested that BM88 forms a dimer of two identical polypeptides linked by disulfide bridges. BM88 has a central proline-rich region containing four PxxP motifs, which typically bind SRC homology-3 (SH3) domains, as well as a putative C-terminal transmembrane region, and several potential sites for N-glycosylation, myristoylation and phosphorylation. It is also suggested that a novel signaling mechanism exists by which BM88 interferes with calcium release from inositol 1,4,5-trisphosphate-sensitive stores and exerts anti-proliferative and anti-apoptotic functions. BM88 is an important molecular target for HDAC inhibition, and transcription of BM88 is induced by trichostatin-A.

    基因ID
    51286
    UniProt
    Q8N111
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