HBEGF 抗体 (AA 20-62)
Quick Overview for HBEGF 抗体 (AA 20-62) (ABIN6989545)
抗原
See all HBEGF 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 20-62
-
交叉反应
- 人
-
预测反应
- Mouse,Rat,Cow,Sheep,Pig
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human DTSF/HB-EGF
-
亚型
- IgG
-
-
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 51-150) antibody
HBEGF 适用: 人, 小鼠, 大鼠 ELISA, IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 21-160) antibodyHBEGF 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (EGF Like Domain) antibody (Biotin)HBEGF 适用: 人 WB, ELISA, IP, ICC, IF 宿主: 小鼠 Monoclonal 4G10 Biotin
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (Bound), (EGF Like Domain), (Soluble) antibodyHBEGF 适用: 人 WB, ELISA, IP, ICC, IF 宿主: 小鼠 Monoclonal 4G10 unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 63-148) antibodyHBEGF 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (AA 21-160) antibodyHBEGF 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal D2 unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) (N-Term) antibodyHBEGF 适用: 人, 小鼠, 大鼠, Cow, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) antibodyHBEGF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Heparin-Binding EGF-Like Growth Factor (HBEGF) antibodyHBEGF 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
-
-
应用备注
-
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
-
别名
- DTSF/HB-EGF
-
背景
-
Synonyms: HB EGF, Diphtheria toxin receptor, DT R, DT-R, DTR, DTS, DTSF, HB-EGF, HBEGF, HBEGF_HUMAN, HEGFL, heparin binding EGF like growth factor, Heparin binding epidermal growth factor, Heparin binding epidermal growth factor like growth factor, Heparin-binding EGF-like growth factor, Proheparin binding EGF like growth factor.
Background: Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a 22 kDa O-glycosylated protein that is a potent mitogen and chemoattractant for vascular smooth muscle cells, fibroblasts and epithelial cells but not endothelial cells. The natural protein has an apparent molecular mass of 19-23 kDa and exists in multiple forms as a result of heterogeneous O-glycosylation and/or Nterminal truncation. HB-EGF is synthesized as a membrane-anchored precursor(proHB-EGF) that is proteolytically cleaved to release the soluble mature growth factor. The two forms are active as juxtacrine and paracrine/autocrine growth factors respectively.HB-EGF activates two EGF receptor subtypes, HER1/ErbB1 and HER4 and binds to heparan sulfate proteoglycan.
-
基因ID
- 1839
-
UniProt
- Q99075
-
途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
-
