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Bcl-2 抗体 (AA 51-150)

This anti-Bcl-2 antibody is a 小鼠 单克隆 antibody detecting Bcl-2 in WB. Suitable for 人, 小鼠, 大鼠, Pig, 兔, 绵羊, 犬, Cow, 豚鼠 和 马.
产品编号 ABIN6989460
发货至: 中国

Quick Overview for Bcl-2 抗体 (AA 51-150) (ABIN6989460)

抗原

See all Bcl-2 (BCL2) 抗体
Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

适用

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人, 小鼠, 大鼠, Pig, 兔, 绵羊, 犬, Cow, 豚鼠, 马

宿主

  • 362
  • 150
  • 4
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  • 1
小鼠

克隆类型

  • 332
  • 186
单克隆

标记

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This Bcl-2 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

4D10
  • 抗原表位

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    AA 51-150

    交叉反应

    Cow, 犬, 豚鼠, 马, 人, 小鼠, Pig, 兔, 大鼠, 绵羊

    纯化方法

    Purified by Protein G.

    免疫原

    KLH conjugated synthetic peptide derived from human Bcl-2

    亚型

    IgG
  • 应用备注

    WB 1:300-5000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))

    别名

    Bcl-2

    背景

    Synonyms: Apoptosis regulator Bcl 2, Apoptosis regulator Bcl2, AW986256, B cell CLL/lymphoma 2, B cell leukemia/lymphoma 2, B cell lymphoma 2, Bcl 2, Bcl-2, Bcl2, BCL2 protein, C430015F12Rik, D630044D05Rik, D830018M01Rik, Leukemia/lymphoma, B-cell, 2, Oncogene B-cell leukemia 2, BCL2_HUMAN.

    Background: The Bcl-2 gene was isolated at the chromosomal breakpoint of t(14,18)-bearing follicular B cell lymphomas(1,2).Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal (3,5).Bcl-2 appears to function in several subcellular locations yet lacks any known motifs that would confer insight into its mechanism of action (6,7).A more recently identified protein,designated Bax p21(i.e., Bcl-associated X protein ),has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2(8). Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activty of Bcl-2(8).

    基因ID

    596

    UniProt

    P10415

    途径

    MAPK Pathway, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
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