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PARP1 抗体 (AA 81-390)

This 兔 多克隆 anti-PARP1 antibody specifically detects PARP1 in WB, ELISA, IHC (p) 和 IF (cc). The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN6989124
发货至: 中国
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北京 101111
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Room 801-803
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Quick Overview for PARP1 抗体 (AA 81-390) (ABIN6989124)

抗原

See all PARP1 抗体
PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This PARP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

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    AA 81-390

    特异性

    KO-Validated

    交叉反应

    人, 大鼠

    预测反应

    Mouse

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 81-390 of human PARP1 (NP_001609.2).

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))

    别名

    PARP1

    背景

    Synonyms: ADPRT,ADPRT 1,ADPRT1,ARTD1,PARP,PARP-1,PPOL,pADPRT-1,PARP1,Cleaved PARP,PARP1

    Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

    基因ID

    142

    UniProt

    P09874

    途径

    Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
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