PARP1 抗体 (AA 581-650) (PE)
Quick Overview for PARP1 抗体 (AA 581-650) (PE) (ABIN6988516)
抗原
See all PARP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 581-650
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Cow,Sheep,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PARP1
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亚型
- IgG
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应用备注
- FCM 1:20-100
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
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别名
- PARP1
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背景
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Synonyms: RANTES, CCL5, TCP228, Small Inducible Cytokine A5, CCL5, SISd, MGC17164, SCYA5, RANTES, D17S136E, SIS-delta, chemokine (C-C motif) ligand 5, regulated on activation normal T cell expressed and secreted, chemokine (C-C motif) ligand 5, T-cell-specific protein RANTES, C-C motif chemokine 5, EoCP, Eosinophil chemotactic cytokine, RANTES(3-68), RANTES(4-68), CCL5_HUMAN,
Background: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils.
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基因ID
- 6352
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UniProt
- P09874
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途径
- Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
抗原
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