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PRKACA 抗体 (AA 1-100) (HRP)

PRKACA 适用: 人, 小鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal HRP
产品编号 ABIN6987978
发货至: 中国
  • 抗原 See all PRKACA 抗体
    PRKACA (Protein Kinase A, alpha (PRKACA))
    抗原表位
    • 15
    • 9
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    适用
    • 52
    • 35
    • 13
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    人, 小鼠
    宿主
    • 57
    • 8
    • 2
    • 1
    克隆类型
    • 61
    • 7
    多克隆
    标记
    • 38
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PRKACA antibody is conjugated to HRP
    应用范围
    • 54
    • 29
    • 17
    • 13
    • 13
    • 9
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Sheep,Pig,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human cAMP Protein Kinase Catalytic subunit
    亚型
    IgG
    Top Product
    Discover our top product PRKACA Primary Antibody
  • 应用备注
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    PRKACA (Protein Kinase A, alpha (PRKACA))
    别名
    PRKACA (PRKACA 产品)
    别名
    PKACA antibody, Calpha antibody, Cs-PKA antibody, PKCA1 antibody, PKA antibody, PKCD antibody, Pkaca antibody, zgc:158799 antibody, protein kinase cAMP-activated catalytic subunit alpha antibody, protein kinase, cAMP dependent, catalytic, alpha antibody, cAMP-dependent protein kinase catalytic subunit antibody, protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a antibody, PRKACA antibody, Prkaca antibody, kin-1 antibody, prkacaa antibody
    背景

    Synonyms: cAMP Protein Kinase Catalytic subunit, cAMP dependent protein kinase alpha catalytic subunit, cAMP dependent protein kinase beta catalytic subunit, cAMP dependent protein kinase catalytic beta subunit isoform 4ab, cAMP dependent protein kinase catalytic subunit alpha, cAMP dependent protein kinase catalytic subunit alpha, isoform 1, cAMP dependent protein kinase catalytic subunit beta, DKFZp781I2452, MGC102831, MGC41879, MGC48865, MGC9320, PKA C alpha, PKA C beta, PKACA, PKACB, PRKACB, Protein kinase A catalytic subunit alpha, Protein kinase A catalytic subunit, Protein kinase A catalytic subunit beta, Protein kinase cAMP dependent catalytic alpha, Protein kinase cAMP dependent catalytic beta, Protein kinase, cAMP dependent, catalytic, alpha, Protein kinase, cAMP dependent, catalytic, beta.

    Background: This gene encodes one of the catalytic subunits of protein kinase A, which exists as a tetrameric holoenzyme with two regulatory subunits and two catalytic subunits, in its inactive form. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. cAMP-dependent phosphorylation of proteins by protein kinase A is important to many cellular processes, including differentiation, proliferation, and apoptosis. Constitutive activation of this gene caused either by somatic mutations, or genomic duplications of regions that include this gene, have been associated with hyperplasias and adenomas of the adrenal cortex and are linked to corticotropin-independent Cushing's syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. Tissue-specific isoforms that differ at the N-terminus have been described, and these isoforms may differ in the post-translational modifications that occur at the N-terminus of some isoforms. [provided by RefSeq, Jan 2015]

    基因ID
    5566
    UniProt
    P17612
    途径
    NF-kappaB Signaling, Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Signaling Events mediated by VEGFR1 and VEGFR2, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGFR1 Specific Signals, Lipid Metabolism, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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