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HBEGF 抗体 (AA 20-62) (Biotin)

This anti-HBEGF antibody is a 兔 多克隆 antibody detecting HBEGF in ELISA, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN6982958
发货至: 中国

Quick Overview for HBEGF 抗体 (AA 20-62) (Biotin) (ABIN6982958)

抗原

See all HBEGF 抗体
HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

适用

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宿主

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克隆类型

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多克隆

标记

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This HBEGF antibody is conjugated to Biotin

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 20-62

    交叉反应

    预测反应

    Mouse,Rat,Cow,Sheep,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human DTSF/HB-EGF

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))

    别名

    DTSF/HB-EGF

    背景

    Synonyms: HB EGF, Diphtheria toxin receptor, DT R, DT-R, DTR, DTS, DTSF, HB-EGF, HBEGF, HBEGF_HUMAN, HEGFL, heparin binding EGF like growth factor, Heparin binding epidermal growth factor, Heparin binding epidermal growth factor like growth factor, Heparin-binding EGF-like growth factor, Proheparin binding EGF like growth factor.

    Background: Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a 22 kDa O-glycosylated protein that is a potent mitogen and chemoattractant for vascular smooth muscle cells, fibroblasts and epithelial cells but not endothelial cells. The natural protein has an apparent molecular mass of 19-23 kDa and exists in multiple forms as a result of heterogeneous O-glycosylation and/or Nterminal truncation. HB-EGF is synthesized as a membrane-anchored precursor(proHB-EGF) that is proteolytically cleaved to release the soluble mature growth factor. The two forms are active as juxtacrine and paracrine/autocrine growth factors respectively.HB-EGF activates two EGF receptor subtypes, HER1/ErbB1 and HER4 and binds to heparan sulfate proteoglycan.

    基因ID

    1839

    UniProt

    Q99075

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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