JNK1/2 抗体 (AA 131-230) (Alexa Fluor 750)
-
- 抗原 See all JNK1/2 products
- JNK1/2
-
抗原表位
- AA 131-230
- 适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This JNK1/2 antibody is conjugated to Alexa Fluor 750
-
应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Sheep,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human JNK1+JNK2
- 亚型
- IgG
-
anti-JNK1/2 (AA 311-424) antibody
适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- JNK1/2
- 别名
- JNK1+JNK2 (JNK1/2 产品)
- 背景
-
Synonyms: JNK1 + JNK2, JNK1 + 2, JNK1/2, c Jun N terminal kinase 1, JNK1, JNK2, JAK 1A, JAK1A, JNK 1, JNK 46, JNK, JNK1A2, JNK21B1/2, MAPK 8, MAPK8, Mitogen activated protein kinase 8, PRKM 8, PRKM8, Protein kinase JNK1, SAPK 1, SAPK gamma, SAPK1, c-Jun, Stress activated protein kinase JNK1, Tyrosine protein kinase JAK1, MK08_HUMAN.
Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Five alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jun 2013]
- 基因ID
- 5599
- UniProt
- P45983
-
