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IL4 Receptor 抗体 (AA 111-210) (Alexa Fluor 647)

IL4R 适用: 小鼠, 大鼠 WB, FACS 宿主: 兔 Polyclonal Alexa Fluor 647
产品编号 ABIN6980477
发货至: 中国
  • 抗原 See all IL4 Receptor (IL4R) 抗体
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    抗原表位
    • 15
    • 15
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 111-210
    适用
    • 53
    • 36
    • 21
    小鼠, 大鼠
    宿主
    • 66
    • 9
    • 2
    • 2
    • 1
    克隆类型
    • 71
    • 8
    • 1
    多克隆
    标记
    • 44
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This IL4 Receptor antibody is conjugated to Alexa Fluor 647
    应用范围
    • 73
    • 24
    • 23
    • 15
    • 14
    • 13
    • 9
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS)
    交叉反应
    小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from rat IL-4R
    亚型
    IgG
    Top Product
    Discover our top product IL4R Primary Antibody
  • 应用备注
    FCM 1:20-100
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    IL4 Receptor (IL4R) (Interleukin 4 Receptor (IL4R))
    别名
    IL-4R (IL4R 产品)
    别名
    IL4R antibody, il-4ra antibody, zgc:113063 antibody, CD124 antibody, IL-4RA antibody, IL4RA antibody, Il4ra antibody, IL4 antibody, Il4r antibody, interleukin 4 receptor antibody, interleukin 4 receptor, tandem duplicate 1 antibody, interleukin 4 receptor, alpha antibody, IL4R antibody, il4r.1 antibody, Il4r antibody, Il4ra antibody
    背景

    Synonyms: Interleukin-4 Receptor, 582J2.1, CD124, CD-124, CD 124, IL 4R alpha, IL4RA, Interleukin 4 receptor alpha chain, MGC118473.

    Background: This gene encodes the alpha chain of the interleukin-4 receptor, a type I transmembrane protein that can bind interleukin4 and interleukin 13 to regulate IgE production. The encoded protein also can bind interleukin 4 to promote differentiation of Th2 cells. A soluble form of the encoded protein can be produced by an alternate splice variant or by proteolysis of the membrane-bound protein, and this soluble form can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. Allelic variations in this gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema. Two transcript variants encoding different isoforms, a membrane-bound and a soluble form, have been found for this gene. [provided by RefSeq, Jul 2008].

    基因ID
    25084
    UniProt
    Q63257
    途径
    JAK/STAT Signaling, Positive Regulation of Immune Effector Process
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