IRS1 抗体 (pTyr1179) (AbBy Fluor® 594)
Quick Overview for IRS1 抗体 (pTyr1179) (AbBy Fluor® 594) (ABIN6979685)
抗原
See all IRS1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr1179
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthesised phosphopeptide derived from human IRS1 around the phosphorylation site of Ser1179.
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亚型
- IgG
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应用备注
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FCM 1:20-100
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- IRS1 (Insulin Receptor Substrate 1 (IRS1))
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别名
- IRS1
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背景
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Synonyms: IRS1 (phospho S1179), p-IRS1 (phospho S1179), p-IRS1, IRS1(phospho-Ser1179), HIRS 1, HIRS1, Insulin Receptor Substrate 1, IRS-1, IRS 1, IRS1, OTTHUMP00000164234, IRS1_HUMAN.
Background: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit.
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基因ID
- 3667
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UniProt
- P35568
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途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Negative Regulation of Hormone Secretion, Response to Growth Hormone Stimulus, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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