PUF60 抗体 (AA 1-100) (Alexa Fluor 350)
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- 抗原 See all PUF60 抗体
- PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))
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抗原表位
- AA 1-100
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PUF60 antibody is conjugated to Alexa Fluor 350
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human PUF60
- 亚型
- IgG
- Top Product
- Discover our top product PUF60 Primary Antibody
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anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (C-Term) antibody
PUF60 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (C-Term) antibodyVerified PUF60 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (AA 243-542) antibodyPUF60 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) antibodyPUF60 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (AA 1-516) antibodyPUF60 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1C1 unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (C-Term) antibodyPUF60 适用: 人 WB, IF, IHC (p), ICC, IHC (wm) 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) antibodyPUF60 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (C-Term) antibodyPUF60 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 斑马鱼, 小鸡, 非洲爪蟾, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (AA 371-420) antibodyPUF60 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 豚鼠, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Poly-U Binding Splicing Factor 60KDa (PUF60) (AA 1-100) antibodyPUF60 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PUF60 (Poly-U Binding Splicing Factor 60KDa (PUF60))
- 别名
- PUF60 (PUF60 产品)
- 别名
- FIR antibody, RoBPI antibody, SIAHBP1 antibody, fc21a05 antibody, wu:fc21a05 antibody, wu:fi43a08 antibody, 2410104I19Rik antibody, 2810454F19Rik antibody, Siahbp1 antibody, fe37c05 antibody, repressor antibody, si:ch211-12p8.2 antibody, si:zc12p8.2 antibody, wu:fb33e11 antibody, wu:fe37c05 antibody, zgc:86806 antibody, poly(U) binding splicing factor 60 antibody, poly-U binding splicing factor a antibody, poly-U binding splicing factor 60 antibody, poly-U binding splicing factor b antibody, PUF60 antibody, puf60a antibody, Puf60 antibody, puf60b antibody
- 背景
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Synonyms: 60 kDa poly(U)-binding-splicing factor, FBP-interacting repressor, FIR, FLJ31379, FUSE-binding protein-interacting repressor, Poly U binding splicing factor 60KDa, Poly(U)-binding-splicing factor PUF60, poly-U binding splicing factor PUF60, PUF60, PUF60_HUMAN, pyrimidine tract binding splicing factor, Ro ribonucleoprotein-binding protein 1, Ro-binding protein 1, RoBP1, RoBPI, siah binding protein 1, Siah-binding protein 1, Siah-BP1, SIAHBP1
Background: DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH basal transcription factor. Represses FUBP1-induced transcriptional activation but not basal transcription. Decreases ERCC3 helicase activity. Does not repress TFIIH-mediated transcription in xeroderma pigmentosum complementation group B (XPB) cells. Is also involved in pre-mRNA splicing. Promotes splicing of an intron with weak 3'-splice site and pyrimidine tract in a cooperative manner with U2AF2. Involved in apoptosis induction when overexpressed in HeLa cells. Isoform 6 failed to repress MYC transcription and inhibited FIR-induced apoptosis in colorectal cancer. Isoform 6 may contribute to tumor progression by enabling increased MYC expression and greater resistance to apoptosis in tumors than in normal cells. Modulates alternative splicing of several mRNAs. Binds to relaxed DNA of active promoter regions. Binds to the pyrimidine tract and 3'-splice site regions of pre-mRNA, binding is enhanced in presence of U2AF2. Binds to Y5 RNA in association with TROVE2. Binds to poly(U) RNA.
- 基因ID
- 22627
- UniProt
- Q9UHX1
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