PARP1 抗体 (N-Term)
Quick Overview for PARP1 抗体 (N-Term) (ABIN6972484)
抗原
See all PARP1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
产品特性
- PARP-1 N-terminal (ADPRT) encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, that modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation and tumor transformation. It also plays a role in the regulation of the molecular events involved in the recovery of cells from DNA damage. Cleavage of PARP-1 (ADPRT) occurs following caspase activation during apoptosis. For additional information on PARP-1, please see the review article PARP-1: An Abundant and Ubiquitous Protein with Roles in Many Cellular Processes in the Targets & Applications section of our website. PARP-1 N-terminal antibody (pAb) was raised in a Rabbit host. It has been validated for use in ChIP-Seq, Immunoprecipitation and Western blot, it has been shown to react with Human samples.
-
纯化方法
- Protein A Chromatography
-
免疫原
- This antibody was raised against a His-Tagged fusion protein corresponding to the N-terminal half of human PARP-1.
-
亚型
- IgG
-
-
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 81-390) antibody
PARP1 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibodyKO Validated PARP1 适用: 人 WB, IP, IF, ICC, IHC (p), ChIP 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 201-300) antibodyPARP1 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 661-881) antibodyPARP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 1-100) antibodyPARP1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G4 unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (AA 670-858) antibodyPARP1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) antibodyPARP1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Monoclonal 8C7 unconjugated Recombinant Antibody
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (cleaved) antibodyPARP1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (N-Term) antibodyPARP1 适用: 人 WB, IHC, 2D-PAGE 宿主: 兔 Polyclonal unconjugated
anti-Poly (ADP-Ribose) Polymerase 1 (PARP1) (C-Term) antibodyPARP1 适用: 人 WB, 2D-PAGE 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
-
-
- PARP1 (Poly (ADP-Ribose) Polymerase 1 (PARP1))
-
别名
- PARP-1
-
分子量
- 120 kDa
-
NCBI登录号
- NP_001609
-
途径
- Apoptosis, Caspase Cascade in Apoptosis, DNA Damage Repair, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location
抗原
-
