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CTCF 抗体

This anti-CTCF antibody is a 兔 多克隆 antibody detecting CTCF in WB, ELISA, IF, ChIP 和 ChIP-seq. Suitable for 人.
产品编号 ABIN6952397
发货至: 中国

Quick Overview for CTCF 抗体 (ABIN6952397)

抗原

See all CTCF 抗体
CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

适用

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宿主

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克隆类型

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多克隆

标记

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This CTCF antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Chromatin Immunoprecipitation (ChIP), ChIP DNA-Sequencing (ChIP-seq)

质量等级

ChIP-seq Grade
  • 特异性

    Polyclonal antibody raised in rabbit against human CTCF (CCCTC-Binding Factor), using 4 KLH coupled peptides.

    交叉反应

    小鼠

    纯化方法

    Peptide affinity purified

    免疫原

    synthetic peptide
  • 应用备注

    ChIP/ChIP-seq 1 μg:ChIP
    ELISA 1:10,000
    WB 1:1,000
    IF 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.5 μg/μL

    缓冲液

    PBS, 0.05 % azide, 0.05 % ProClin300

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • 抗原

    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))

    别名

    CTCF

    背景

    CTCF (UniProt/Swiss-Prot entry P49711) is a transcriptional regulator protein with 11 highly conserved zinc finger domains. By using different combinations of the zinc finger domains, CTCF can bind to different DNA sequences and proteins. As such it can act as both a transcriptional repressor and a transcriptional activator. By binding to transcriptional insulator elements, CTCF can also block communication between enhancers and upstream promoters, thereby regulating imprinted gene expression. CTCF also binds to the H19 imprinting control region and mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to IGF2. Mutations in the CTCF gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumor.

    UniProt

    P49711
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