Transferrin Receptor 2 抗体
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- 抗原 See all Transferrin Receptor 2 (TFR2) 抗体
- Transferrin Receptor 2 (TFR2)
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This Transferrin Receptor 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within human Transferrin Receptor 2 aa 100-300.
- 克隆位点
- 1G4
- 亚型
- IgG
- Top Product
- Discover our top product TFR2 Primary Antibody
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anti-Transferrin Receptor 2 (TFR2) (AA 4-87) antibody
TFR2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transferrin Receptor 2 (TFR2) (AA 211-405) antibodyTFR2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transferrin Receptor 2 (TFR2) (AA 86-259) antibodyTFR2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transferrin Receptor 2 (TFR2) (AA 534-605) antibodyTFR2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transferrin Receptor 2 (TFR2) (AA 582-801) antibodyTFR2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transferrin Receptor 2 (TFR2) antibodyTFR2 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transferrin Receptor 2 (TFR2) (AA 493-784) antibodyTFR2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transferrin Receptor 2 (TFR2) (AA 604-703) antibodyTFR2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transferrin Receptor 2 (TFR2) (AA 493-785) antibodyTFR2 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transferrin Receptor 2 (TFR2) antibodyTFR2 适用: 人, 小鼠, 大鼠, 猴 WB, IF, FACS 宿主: 小鼠 Monoclonal 2B4 unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- Transferrin Receptor 2 (TFR2)
- 别名
- TFR2 (TFR2 产品)
- 别名
- TFR2 antibody, Trfr2 antibody, HFE3 antibody, TFRC2 antibody, zgc:123043 antibody, transferrin receptor 2 antibody, TFR2 antibody, Tfr2 antibody, tfr2 antibody
- 背景
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Synonyms: Transferrin receptor protein 2, TFR2, HFE3
Background: Iron is a vital molecule for living organisms because it is involved in a wide variety of metabolic processes, such as oxygen transport, DNA synthesis and electron transport. Excessive iron uptake leads to tissue damage as a result of formation of free radicals. Iron uptake and storage is tightly regulated by the feedback system of iron responsive element-containing gene products and iron regulatory proteins that modulate the expression levels of the genes involved in iron metabolism. The transferrin receptor 2 (TFR2) mediates the uptake of transferrin-bound iron. It is involved in iron metabolism, hepatocyte function and erythrocyte differentiation, and is highly expressed as a protein in liver as well as in hepatocytes and erythroid precursors. The gene encoding human TRF2 maps to chromosome 7q22 and is expressed as an a isoform, which encodes a transmembrane protein, and a b isoform, which encodes a shorter, intracellular protein. Mutations in the TFR2 gene result in hereditary hemochromatosis type III (HFE3), an iron overloading disorder that results in clinical complications, including cirrhosis, cardiopathy, diabetes, endocrine dysfunctions, arthropathy and susceptibility to liver cancer.
- 基因ID
- 7036
- UniProt
- Q9UP52
- 途径
- Transition Metal Ion Homeostasis
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