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TBP 抗体

The 小鼠 单克隆 anti-TBP antibody (Clone 2C9) (ABIN6945137) specifically detects TBP in WB 和 ChIP-seq. The antibody is reactive with 人 samples.
产品编号 ABIN6945137
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for TBP 抗体 (ABIN6945137)

抗原

See all TBP 抗体
TBP (TATA Box Binding Protein (TBP))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This TBP antibody is un-conjugated

应用范围

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Western Blotting (WB), ChIP DNA-Sequencing (ChIP-seq)

克隆位点

2C9
  • 交叉反应

    纯化方法

    Monoclonal antibody in PBS containing 0.05% azide, purified by ammonium sulphate precipitation followed by dialysis

    免疫原

    Monoclonal antibody raised in mouse against the amino-terminal domain of human TBP (TATA box binding protein).

    亚型

    IgG1
  • 应用备注

    WB 1:300-5000
    ChIP-seq()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    8 μg/μL

    缓冲液

    PBS with 0.05 % sodium azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    TBP (TATA Box Binding Protein (TBP))

    别名

    TBP

    背景

    Synonyms: GTF2D, GTF2D1, SCA17, TF2D, TFIID

    Background: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID (PubMed:2374612, PubMed:2363050, PubMed:2194289, PubMed:9836642, PubMed:27193682). Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II (PubMed:2374612, PubMed:2363050, PubMed:2194289, PubMed:9836642, PubMed:27193682). Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III (PubMed:26638071). Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription (PubMed:15970593). The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

    基因ID

    6908

    UniProt

    P20226

    途径

    WNT signaling
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