TBP 抗体
Quick Overview for TBP 抗体 (ABIN6945137)
抗原
See all TBP 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人
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纯化方法
- Monoclonal antibody in PBS containing 0.05% azide, purified by ammonium sulphate precipitation followed by dialysis
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免疫原
- Monoclonal antibody raised in mouse against the amino-terminal domain of human TBP (TATA box binding protein).
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亚型
- IgG1
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应用备注
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WB 1:300-5000
ChIP-seq() -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 8 μg/μL
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缓冲液
- PBS with 0.05 % sodium azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- TBP (TATA Box Binding Protein (TBP))
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别名
- TBP
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背景
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Synonyms: GTF2D, GTF2D1, SCA17, TF2D, TFIID
Background: General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID (PubMed:2374612, PubMed:2363050, PubMed:2194289, PubMed:9836642, PubMed:27193682). Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II (PubMed:2374612, PubMed:2363050, PubMed:2194289, PubMed:9836642, PubMed:27193682). Component of a BRF2-containing transcription factor complex that regulates transcription mediated by RNA polymerase III (PubMed:26638071). Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (pre-initiation complex) during RNA polymerase I-dependent transcription (PubMed:15970593). The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
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基因ID
- 6908
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UniProt
- P20226
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途径
- WNT signaling
抗原
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