SRP54 抗体
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- 抗原 See all SRP54 抗体
- SRP54 (Signal Recognition Particle 54kDa (SRP54))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This SRP54 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within human SRP54 aa 1-200.
- 克隆位点
- 1A4
- 亚型
- IgG
- Top Product
- Discover our top product SRP54 Primary Antibody
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anti-Signal Recognition Particle 54kDa (SRP54) antibody
SRP54 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Signal Recognition Particle 54kDa (SRP54) (AA 1-504) antibodySRP54 适用: 人 ELISA, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle 54kDa (SRP54) (AA 1-100) antibodySRP54 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2G7 unconjugated
anti-Signal Recognition Particle 54kDa (SRP54) (AA 346-374) antibodySRP54 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle 54kDa (SRP54) (AA 196-455) antibodySRP54 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle 54kDa (SRP54) antibodySRP54 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle 54kDa (SRP54) (AA 391-440) antibodySRP54 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle 54kDa (SRP54) (AA 182-231) antibodySRP54 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Signal Recognition Particle 54kDa (SRP54) (Middle Region) antibodySRP54 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, 山羊 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IP(1-2 μg) - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- SRP54 (Signal Recognition Particle 54kDa (SRP54))
- 别名
- SRP54 (SRP54 产品)
- 别名
- Srp54k antibody, zgc:55842 antibody, zgc:85713 antibody, SRP54 antibody, signal recognition particle 54 antibody, signal recognition particle protein antibody, signal recognition particle subunit Srp54 antibody, signal recognition particle antibody, family with sequence similarity 177 member A1 antibody, signal recognition particle 54kDa S homeolog antibody, signal recognition particle 54kDa antibody, SRP54 antibody, srp54 antibody, SSO_RS04840 antibody, MA_RS23935 antibody, AF_RS03170 antibody, PAB_RS02540 antibody, MSP_RS07670 antibody, RCI_RS04175 antibody, TGAM_RS09885 antibody, MTBMA_RS08340 antibody, FAM177A1 antibody, srp54.S antibody, Srp54 antibody
- 背景
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Synonyms: Signal recognition particle 54 kDa protein, SRP54
Background: SRP54, a component of the signal recognition particle (SRP), recognizes the signal peptide of secretory proteins and interacts with the signal recognition particle receptor to target the ribosome and the associated nascent chain to the endoplasmic reticulum. By functional analysis showed that SRP54 binds to SRP RNA via the M-domain, but only in the presence of RNA-bound SRP19, and that it associates with the signal peptide of nascent polypeptide chains. RNA interaction requires the presence of a loop in the C-terminal M-domain. Signal peptide recognition most likely involves methionine-rich loops. During signal peptide recognition, SRP54 is positioned at the exit site close to ribosomal proteins L23a and L35. When SRP54 contacts the signal recognition particle receptor, SRP54 is rearranged such that it is no longer close to L23a. This repositioning may allow the translocon to dock with the ribosome, leading to insertion of the signal peptide into the translocation channel.
- 基因ID
- 6729
- UniProt
- P61011
- 途径
- SARS-CoV-2 Protein Interactome
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