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SFPQ 抗体

SFPQ 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Monoclonal 2C6 unconjugated
产品编号 ABIN6944866
发货至: 中国
  • 抗原 See all SFPQ 抗体
    SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
    适用
    • 48
    • 22
    • 17
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 46
    • 2
    克隆类型
    • 38
    • 10
    单克隆
    标记
    • 27
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SFPQ antibody is un-conjugated
    应用范围
    • 35
    • 20
    • 14
    • 10
    • 9
    • 8
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Recombinant protein within Human SFPQ aa 600 to the C-terminus
    克隆位点
    2C6
    亚型
    IgG
    Top Product
    Discover our top product SFPQ Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SFPQ (Splicing Factor Proline/glutamine-Ric (SFPQ))
    别名
    SFPQ (SFPQ 产品)
    别名
    1110004P21Rik antibody, 2810416M14Rik antibody, 5730453G22Rik antibody, 9030402K04Rik antibody, AU021830 antibody, D4Ertd314e antibody, Gm12940 antibody, OTTMUSG00000009329 antibody, PSF antibody, REP1 antibody, hm:zeh0027 antibody, wu:fa11h12 antibody, wu:fd10f03 antibody, zgc:85935 antibody, POMP100 antibody, splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) antibody, splicing factor proline/glutamine-rich antibody, splicing factor proline and glutamine rich antibody, Sfpq antibody, sfpq antibody, SFPQ antibody
    背景

    Synonyms: Splicing factor proline- and glutamine-rich, 100 kDa DNA-pairing protein, DNA-binding p52/p100 complex 100 kDa subunit, Polypyrimidine tract-binding protein-associated-splicing factor, hPOMp100, PSF, PTB-associated-splicing factor, SFPQ.

    Background: DNA- and RNA binding protein, involved in several nuclear processes. Essential pre-mRNA splicing factor required early in spliceosome formation and for splicing catalytic step II, probably as a heteromer with NONO. Binds to pre-mRNA in spliceosome C complex, and specifically binds to intronic polypyrimidine tracts. Involved in regulation of signal-induced alternative splicing. Interacts with U5 snRNA, probably by binding to a purine-rich sequence located on the 3' side of U5 snRNA stem 1b. May be involved in a pre-mRNA coupled splicing and polyadenylation process as component of a snRNP-free complex with SNRPA/U1A. The SFPQ-NONO heteromer associated with MATR3 may play a role in nuclear retention of defective RNAs. SFPQ may be involved in homologous DNA pairing, in vitro, promotes the invasion of ssDNA between a duplex DNA and produces a D-loop formation.

    基因ID
    6421
    UniProt
    P23246
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