RPE65 抗体
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- 抗原 See all RPE65 抗体
- RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This RPE65 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Human RPE65 aa 450 to the C-terminus
- 克隆位点
- 2C1
- 亚型
- IgG
- Top Product
- Discover our top product RPE65 Primary Antibody
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anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) antibody
RPE65 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) (AA 348-484) antibodyRPE65 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) (AA 274-533) antibodyRPE65 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) (Internal Region) antibodyVerified RPE65 适用: 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) antibodyRPE65 适用: 人, 小鼠, Cow, Pig, 小鸡, 非洲爪蟾 WB, IHC, IF, ICC, FACS 宿主: 小鼠 Monoclonal 401-8B11-3D9 unconjugated
anti-Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65) antibodyRPE65 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 7B10 unconjugated Recombinant Antibody
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- 应用备注
- WB 1:300-5000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- RPE65 (Retinal Pigment Epithelium-Specific Protein 65kDa (RPE65))
- 别名
- RPE65 (RPE65 产品)
- 别名
- LCA2 antibody, RP20 antibody, mRPE65 antibody, rd12 antibody, sRPE65 antibody, 65kDa antibody, A930029L06Rik antibody, Mord1 antibody, DRPE65 antibody, RPE65 antibody, anon-WO0148162.1 antibody, anon-WO0148163.1 antibody, beta-diox antibody, DmelCG9347 antibody, CG9347 antibody, MGC52887 antibody, MGC154296 antibody, MGC85437 antibody, rpe65 antibody, RPE56c antibody, si:ch211-198n5.12 antibody, 13cIMH antibody, RPE56b antibody, rpepb antibody, si:ch211-198n5.5 antibody, wu:fc74c09 antibody, zgc:110538 antibody, RPE56a antibody, rpepa antibody, zgc:73213 antibody, RPE65, retinoid isomerohydrolase antibody, retinal pigment epithelium 65 antibody, neither inactivation nor afterpotential B antibody, retinal pigment epithelium-specific protein 65kDa S homeolog antibody, retinal pigment epithelium-specific protein 65kDa L homeolog antibody, RPE65 homolog antibody, retinal pigment epithelium-specific protein 65kDa antibody, retinal pigment epithelium-specific protein 65c antibody, retinal pigment epithelium-specific protein 65b antibody, retinal pigment epithelium-specific protein 65a antibody, RPE65 antibody, Rpe65 antibody, ninaB antibody, rpe65.S antibody, rpe65.L antibody, rpe65 antibody, rpe65c antibody, rpe65b antibody, rpe65a antibody
- 背景
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Synonyms: Retinoid isomerohydrolase, All-trans-retinyl-palmitate hydrolase, Retinal pigment epithelium-specific 65 kDa protein, Retinol isomerase, RPE65
Background: Critical isomerohydrolase in the retinoid cycle involved in regeneration of 11-cis-retinal, the chromophore of rod and cone opsins. Catalyzes the cleavage and isomerization of all-trans-retinyl fatty acid esters to 11-cis-retinol which is further oxidized by 11-cis retinol dehydrogenase to 11-cis-retinal for use as visual chromophore (PubMed:16116091). Essential for the production of 11-cis retinal for both rod and cone photoreceptors (PubMed:17848510). Also capable of catalyzing the isomerization of lutein to meso-zeaxanthin an eye-specific carotenoid (PubMed:28874556). The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT (By similarity).
- 基因ID
- 6121
- UniProt
- Q16518
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