RHOA 抗体
Quick Overview for RHOA 抗体 (ABIN6944782)
抗原
See all RHOA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- Human RhoA aa 150 to the C-terminus
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亚型
- IgG
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anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-193) antibody
RHOA 适用: 人 WB, ELISA, IHC (p), IF 宿主: 小鼠 Monoclonal 1B12 unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-193) antibodyRHOA 适用: 人 WB, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 1C1 unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 100-150) antibodyRHOA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (C-Term) antibodyRHOA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (pSer188) antibodyRHOA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-194) antibodyRHOA 适用: 人 WB, ELISA, IHC, IHC (p), IF 宿主: 小鼠 Monoclonal 1B12 unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (C-Term) antibodyRHOA 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-193) antibodyKO Validated RHOA 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-191) antibodyRHOA 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ras Homolog Gene Family, Member A (RHOA) (AA 1-193) antibodyRHOA 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
FCM 1:20-100
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- RHOA (Ras Homolog Gene Family, Member A (RHOA))
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别名
- RhoA
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背景
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Synonyms: Transforming protein RhoA, Rho cDNA clone 12, h12, RHOA
Background: Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Involved in a microtubule-dependent signal that is required for the myosin contractile ring formation during cell cycle cytokinesis. Plays an essential role in cleavage furrow formation. Required for the apical junction formation of keratinocyte cell-cell adhesion. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. Stimulates PKN2 kinase activity. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP. Essential for the SPATA13-mediated regulation of cell migration and adhesion assembly and disassembly. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization.
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基因ID
- 387
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UniProt
- P61586
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途径
- Microtubule Dynamics, WNT signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Positive Regulation of Endopeptidase Activity, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, SARS-CoV-2 Protein Interactome
抗原
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