PPARGC1B 抗体
-
- 抗原 See all PPARGC1B 抗体
- PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))
-
适用
- 人, 大鼠
-
宿主
- 兔
-
克隆类型
- 单克隆
-
标记
- This PPARGC1B antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Flow Cytometry (FACS)
- 交叉反应
- 人, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within C-terminal human PGC1 beta
- 克隆位点
- 6H5
- 亚型
- IgG
- Top Product
- Discover our top product PPARGC1B Primary Antibody
-
-
- 应用备注
-
WB 1:300-5000
FCM 1:20-100 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
-
- 抗原
- PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))
- 别名
- PPARGC1B (PPARGC1B 产品)
- 别名
- PPARGC1B antibody, 4631412G21Rik antibody, Perc antibody, PGC1beta antibody, ERRL1 antibody, PERC antibody, PGC-1(beta) antibody, PGC1B antibody, PPARG coactivator 1 beta antibody, peroxisome proliferative activated receptor, gamma, coactivator 1 beta antibody, PPARGC1B antibody, Ppargc1b antibody
- 背景
-
Synonyms: Peroxisome proliferator-activated receptor gamma coactivator 1-beta, PGC-1-related estrogen receptor alpha coactivator, PGC-1-beta, PPAR-gamma coactivator 1-beta, PPARGC-1-beta, PPARGC1B, PERC, PGC1, PGC1B, PPARGC1.
Background: Plays a role of stimulator of transcription factors and nuclear receptors activities. Activates transcriptional activity of estrogen receptor alpha, nuclear respiratory factor 1 (NRF1) and glucocorticoid receptor in the presence of glucocorticoids. May play a role in constitutive non-adrenergic-mediated mitochondrial biogenesis as suggested by increased basal oxygen consumption and mitochondrial number when overexpressed. May be involved in fat oxidation and non-oxidative glucose metabolism and in the regulation of energy expenditure. Induces the expression of PERM1 in the skeletal muscle in an ESRRA-dependent manner.
- 基因ID
- 133522
- UniProt
- Q86YN6
- 途径
- AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha
-