PIWIL1 抗体
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- 抗原 See all PIWIL1 抗体
- PIWIL1 (Piwi-Like 1 (PIWIL1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This PIWIL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Recombinant protein within human PIWIL1 aa 700-850
- 克隆位点
- 12C7
- 亚型
- IgG
- Top Product
- Discover our top product PIWIL1 Primary Antibody
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anti-Piwi-Like 1 (PIWIL1) (AA 551-650) antibody
PIWIL1 适用: 人, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Piwi-Like 1 (PIWIL1) (Internal Region) antibodyVerified PIWIL1 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Piwi-Like 1 (PIWIL1) (N-Term) antibodyPIWIL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Piwi-Like 1 (PIWIL1) (AA 1-861) antibodyPIWIL1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Piwi-Like 1 (PIWIL1) (AA 390-690) antibodyPIWIL1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Piwi-Like 1 (PIWIL1) (Internal Region) antibodyPIWIL1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Piwi-Like 1 (PIWIL1) (C-Term) antibodyPIWIL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Piwi-Like 1 (PIWIL1) (AA 71-120) antibodyPIWIL1 适用: 人, 小鼠, 大鼠, 犬, Cow, 马, 兔, 豚鼠, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Piwi-Like 1 (PIWIL1) antibodyPIWIL1 适用: 人, 小鼠, 大鼠 WB, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- PIWIL1 (Piwi-Like 1 (PIWIL1))
- 别名
- PIWIL1 (PIWIL1 产品)
- 别名
- ziwi antibody, PIWI antibody, HIWI antibody, MIWI antibody, piwi like RNA-mediated gene silencing 1 antibody, PIWI-like protein 1 antibody, putative PIWI-like protein 1 antibody, putative argonaut-like protein antibody, piwi-like RNA-mediated gene silencing 1 antibody, PIWIL1 antibody, Tb10.70.5520 antibody, LINJ_21_0470 antibody, LBRM_21_0470 antibody, piwil1 antibody, Piwil1 antibody
- 背景
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Synonyms: Piwi-like protein 1, PIWIL1, HIWI., MIWI, CT80.1.
Background: Endoribonuclease that plays a central role in postnatal germ cells by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Directly binds methylated piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicer-independent mechanism and are primarily derived from transposons and other repeated sequence elements. Strongly prefers a uridine in the first position of their guide (g1U preference, also named 1U-bias). Not involved in the piRNA amplification loop, also named ping-pong amplification cycle. Acts as an endoribonuclease that cleaves transposon messenger RNAs. Besides their function in transposable elements repression, piRNAs are probably involved in other processes during meiosis such as translation regulation. Probable component of some RISC complex, which mediates RNA cleavage and translational silencing. Also plays a role in the formation of chromatoid bodies and is required for some miRNAs stability. Required to sequester RNF8 in the cytoplasm until late spermatogenesis, RNF8 being released upon ubiquitination and degradation of PIWIL1.
- 基因ID
- 9271
- UniProt
- Q96J94
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