Recombinant PCNA 抗体 (AA 100-200)
Our Local Distributor
北京 101111
Quick Overview for Recombinant PCNA 抗体 (AA 100-200) (ABIN6944453)
抗原
See all PCNA 抗体抗体类型
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 100-200
-
原理
- PCNA Recombinant Antibody
-
交叉反应
- 人, 小鼠, 大鼠
-
纯化方法
- Purified by Protein A.
-
免疫原
- Recombinant human PCNA between 100 to 200 amino acids
-
亚型
- IgG
-
-
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 151-261) antibody
PCNA 适用: 人 WB, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 231-261), (C-Term) antibodyPCNA 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB17486 unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 53-196) antibodyPCNA 适用: 人, 猴 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 7H4F8 unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 53-196) antibodyPCNA 适用: 人, 小鼠, 大鼠 WB, IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 7H4F8 unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 1-261) antibodyPCNA 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 1-261) antibodyPCNA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal S1 unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) antibodyPCNA 适用: 人 WB, IHC, IP, IF, IHC (p), ICC, IHC (fro), FISH 宿主: 兔 Polyclonal unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 1-261) antibodyPCNA 适用: 人 WB, IHC, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 201-261) antibodyPCNA 适用: 人 WB, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Proliferating Cell Nuclear Antigen (PCNA) (AA 6-261) antibodyPCNA 适用: 人, 小鼠, 大鼠, Pig, 犬, 兔, 猕猴 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB(1:300-5000), IHC-P(1:20-100), IHC-F(1:200-400), IF(1:50-200), Flow-Cyt(1 μg/Test), ICC/IF(1:50-100)
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
-
别名
- PCNA
-
背景
-
Synonyms: ProlifeRating cell nuclear antigen, Cyclin, PCNA
Background: Auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2. Plays a key role in DNA damage response (DDR) by being conveniently positioned at the replication fork to coordinate DNA replication with DNA repair and DNA damage tolerance pathways. Acts as a loading platform to recruit DDR proteins that allow completion of DNA replication after DNA damage and promote postreplication repair: Monoubiquitinated PCNA leads to recruitment of translesion (TLS) polymerases, while 'Lys-63'-linked polyubiquitination of PCNA is involved in error-free pathway and employs recombination mechanisms to synthesize across the lesion.
-
基因ID
- 5111
-
UniProt
- P12004
-
途径
- Telomere Maintenance, DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagy
抗原
-
