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Neuregulin 1 抗体 (AA 81-200) (AbBy Fluor® 750)

NRG1 适用: 大鼠 FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 750
产品编号 ABIN6944320
发货至: 中国
  • 抗原 See all Neuregulin 1 (NRG1) 抗体
    Neuregulin 1 (NRG1)
    抗原表位
    • 16
    • 15
    • 15
    • 10
    • 9
    • 9
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 81-200
    适用
    • 99
    • 74
    • 51
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    大鼠
    宿主
    • 115
    • 10
    克隆类型
    • 115
    • 10
    多克隆
    标记
    • 55
    • 11
    • 8
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Neuregulin 1 antibody is conjugated to AbBy Fluor® 750
    应用范围
    • 87
    • 40
    • 38
    • 38
    • 36
    • 36
    • 23
    • 14
    • 12
    • 11
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    大鼠
    预测反应
    Human,Mouse,Cow,Sheep,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Neuregulin-1
    亚型
    IgG
    Top Product
    Discover our top product NRG1 Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Neuregulin 1 (NRG1)
    别名
    NRG1 (NRG1 产品)
    背景

    Synonyms: Acetylcholine receptor-inducing activity, ARIA, Breast cancer cell differentiation factor p45, GGF, Glial growth factor, Heregulin, HGL, HRG, HRG1, HRGA, NDF, Neu differentiation factor, Neuregulin1, NRG 1, Pro-neuregulin-1, membrane-bound isoform, Sensory and motor neuron-derived factor, SMDF, NRG1_HUMAN.

    Background: The protein encoded by this gene is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD). The NRG-1 protein binds to and activates the tyrosine kinases receptors ErbB3 and ErbB4, initiating signaling cascades. NRG-1 has multiple functions, for example, in the brain it regulates various processes such as radial glia formation and neuronal migration, dendritic development, and expression of neurotransmitters receptors, in the peripheral nervous system NRG-1 regulates processes such as target cell differentiation, and Schwann cell survival.

    基因ID
    3084
    UniProt
    Q02297
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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