MYL2 抗体
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- 抗原 See all MYL2 抗体
- MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))
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适用
- 小鼠, 大鼠, 斑马鱼
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This MYL2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 小鼠, 大鼠, 斑马鱼
- 纯化方法
- Purified by Protein A.
- 免疫原
- Human Myosin Light Chain 2 between 150-250 amino acids
- 克隆位点
- 10B7
- 亚型
- IgG
- Top Product
- Discover our top product MYL2 Primary Antibody
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anti-Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) (AA 2-159) antibody
MYL2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) (AA 42-75) antibodyMYL2 适用: 人, 小鼠, 大鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB56979 unconjugated
anti-Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) (AA 1-166) antibodyMYL2 适用: 人 WB, ELISA, IF, IP 宿主: 小鼠 Monoclonal 3B9-B4 unconjugated
anti-Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) (AA 1-166) antibodyMYL2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) antibodyMYL2 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) antibodyMYL2 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) (AA 8-164) antibodyMYL2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) antibodyMYL2 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) (AA 1-166) antibodyMYL2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal AT3B2 unconjugated
anti-Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2) antibodyMYL2 适用: 人, 小鼠, 大鼠, Pig, 兔, Cow, 犬 WB, ELISA, IHC, IF, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal unconjugated
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- 应用备注
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WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- MYL2 (Myosin, Light Chain 2, Regulatory, Cardiac, Slow (MYL2))
- 别名
- Myosin Light Chain 2 (MYL2 产品)
- 别名
- CMH10 antibody, MLC2 antibody, 2410014J02Rik antibody, MLC-2 antibody, Mlc2 antibody, MLC-2v antibody, Mlc2v antibody, Mylpc antibody, Mlc-2 antibody, myl2 antibody, zgc:136848 antibody, XMLC2 antibody, cmh10 antibody, mlc2 antibody, G2 antibody, MLC-2A antibody, MLC2V antibody, myosin light chain 2 antibody, myosin light chain, phosphorylatable, fast skeletal muscle antibody, myosin, light polypeptide 2, regulatory, cardiac, slow antibody, myosin, light chain 2b, regulatory, cardiac, slow antibody, myosin light chain 2 S homeolog antibody, myosin, light chain 2, regulatory, cardiac, slow antibody, MYL2 antibody, Mylpf antibody, Myl2 antibody, myl2b antibody, myl2.S antibody
- 背景
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Synonyms: Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, Cardiac myosin light chain 2, Myosin light chain 2, slow skeletal/ventricular muscle isoform, Ventricular myosin light chain 2, MLC-2, MLC-2v, MLC-2s/v, MYL2
Background: Contractile protein that plays a role in heart development and function (PubMed:10409661). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion, as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin binding sites to sustain thin filament activation as a means to fine-tune myofilament calcium sensitivity to force (By similarity) (PubMed:22426213, PubMed:16908724, PubMed:10409661). During cardiogenesis plays an early role in cardiac contractility by promoting cardiac myofibril assembly (PubMed:9422794).
- 基因ID
- 17906
- UniProt
- P51667
- 途径
- Myometrial Relaxation and Contraction
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