ITPR1 抗体
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- 抗原 See all ITPR1 抗体
- ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This ITPR1 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Human IP3 receptor aa 1770-1900
- 克隆位点
- 5G10
- 亚型
- IgG
- Top Product
- Discover our top product ITPR1 Primary Antibody
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- 应用备注
- IHC-P 1:200-400
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store for 1 year at -20°C from date of shipment.
- 有效期
- 12 months
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- 抗原
- ITPR1 (Inositol 1,4,5-Trisphosphate Receptor, Type 1 (ITPR1))
- 别名
- ITPR1 (ITPR1 产品)
- 别名
- D6Pas2 antibody, ENSMUSG00000072853 antibody, Gm10429 antibody, IP3R1 antibody, InsP3R antibody, Ip3r antibody, Itpr-1 antibody, P400 antibody, Pcp-1 antibody, Pcp1 antibody, opt antibody, I145TR antibody, InsP3R1 antibody, INSP3R1 antibody, IP3R antibody, SCA15 antibody, SCA16 antibody, SCA29 antibody, inositol 1,4,5-trisphosphate receptor type 1 antibody, inositol 1,4,5-trisphosphate receptor 1 antibody, inositol 1,4,5-trisphosphate receptor, type 1 antibody, ITPR1 antibody, Itpr1 antibody
- 背景
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Synonyms: Inositol 1,4,5-trisphosphate receptor type 1, IP3 receptor isoform 1, Type 1 inositol 1,4,5-trisphosphate receptor, IP3R 1, InsP3R1, Type 1 InsP3 receptor, ITPR1, INSP3R1, IP3 Receptor.
Background: Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
- 基因ID
- 3708
- UniProt
- Q14643
- 途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, Synaptic Membrane, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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