NFKBIB 抗体
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北京 101111
Quick Overview for NFKBIB 抗体 (ABIN6943780)
抗原
See all NFKBIB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- IKB beta (9D10) Monoclonal Antibody
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交叉反应
- 人
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纯化方法
- Purified by Protein A.
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免疫原
- Full length protein
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亚型
- IgG
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应用备注
- WB(1:300-5000), IHC-P(1:200-400), IF(ICC)(1:50-200), IHC()
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- NFKBIB (NF-kappa-B inhibitor beta (NFKBIB))
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别名
- IKB beta
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背景
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Synonyms: NF-kappa-B inhibitor beta, I-kappa-B-beta, Thyroid receptor-interacting protein 9, NF-kappa-BIB, IkB-B, IkB-beta, IkappaBbeta, TR-interacting protein 9, TRIP-9, NFKBIB
Background: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.
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基因ID
- 4793
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UniProt
- Q15653
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途径
- NF-kappaB Signaling, Activation of Innate immune Response, Maintenance of Protein Location, Toll-Like Receptors Cascades
抗原
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