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HES1 抗体

This anti-HES1 antibody is a 兔 单克隆 antibody detecting HES1 in WB, IHC, FACS 和 IF (cc). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6943615
发货至: 中国

Quick Overview for HES1 抗体 (ABIN6943615)

抗原

See all HES1 抗体
HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

适用

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人, 小鼠, 大鼠

宿主

  • 68
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克隆类型

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单克隆

标记

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This HES1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))

克隆位点

3F8
  • 交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    Recombinant human Hes1 between 200 to 300 amino acids

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    FCM 1:20-100
    IF(ICC) 1:50-200
    IHC()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

    别名

    Hes1

    背景

    Synonyms: Transcription factor HES-1, Class B basic helix-loop-helix protein 39, Hairy and enhancer of split 1, Hairy homolog, Hairy-like protein, bHLHb39, hHL, HES1

    Background: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.

    基因ID

    3280

    UniProt

    Q14469

    途径

    DNA Damage Repair
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