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HES1 抗体 (AA 41-150)

Name: HES1 抗体 (AA 41-150)
SKU: ABIN682393
Availability: OutOfStock

HES1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

Formalin-fixed and paraffin embedded human kidney tissue labeled with Anti-HES-1 Polyclonal Antibody, Unconjugated (ABIN682393) at 1:200 followed by conjugation to the secondary antibody and DAB staining (HES1 抗体 (AA 41-150))

IHC

Formalin-fixed and paraffin embedded rat brain labeled with Anti-HES1 Polyclonal Antibody, Unconjugated at 1:200 followed by conjugation to the secondary antibody and DAB staining (HES1 抗体 (AA 41-150))

IHC (p)

The relationships of the Wnt and Notch signaling pathway and the proliferation of epidermal stem cells was analyzed by immunofluorescence. (HES1 抗体 (AA 41-150))

IF (cc)

4 images

(3 references)

产品编号 ABIN682393

发货至: 中国

Datasheet as PDF

抗原 See all HES1 抗体

HES1 (Hes Family bHLH Transcription Factor 1 (HES1))
抗原表位
15

12

9

8

7

5

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 41-150
适用
79

50

41

5

4

4

3

3

3

2

2

2

1
人, 小鼠, 大鼠
宿主
73

14

1

1
兔
Compatible Secondaries
克隆类型
65

24
多克隆
标记
50

5

3

3

3

3

3

3

3

3

3

2

1

1

1

1

1
This HES1 antibody is un-conjugated
应用范围
70

34

18

14

13

12

10

6

5

4

4

3

1

1
Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人, 小鼠, 大鼠

预测反应

Cow,Pig,Horse,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human HES1

亚型

IgG

Top Product

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anti-Hes Family bHLH Transcription Factor 1 (HES1) (N-Term) antibody
HES1 适用: 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 豚鼠, 马 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Hes Family bHLH Transcription Factor 1 (HES1) antibody
HES1 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

anti-Hes Family bHLH Transcription Factor 1 (HES1) (AA 9-38) antibody
HES1 适用: 人 WB, ELISA, FACS, IF 宿主: 兔 Polyclonal unconjugated

anti-Hes Family bHLH Transcription Factor 1 (HES1) (AA 1-277) antibody
HES1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Hes Family bHLH Transcription Factor 1 (HES1) (AA 24-35) antibody
HES1 适用: 人, 小鼠, 大鼠, Cow, 兔, 斑马鱼, 马, 猴, Bat, 非洲爪蟾, Hamster WB, IHC, IF, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Hes Family bHLH Transcription Factor 1 (HES1) antibody
HES1 适用: 人 ELISA, LMNX 宿主: 小鼠 Monoclonal OTI1B5 unconjugated

anti-Hes Family bHLH Transcription Factor 1 (HES1) (AA 21-251) antibody
HES1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Hes Family bHLH Transcription Factor 1 (HES1) antibody
HES1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Hes Family bHLH Transcription Factor 1 (HES1) (N-Term) antibody
HES1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Hes Family bHLH Transcription Factor 1 (HES1) antibody
Microarray verified HES1 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB869233 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
Shi, Shu, Yang, Xu, Xing, Liu, Chen, Qi, Liu, Wang, Tang, Xie: "Wnt and Notch signaling pathway involved in wound healing by targeting c-Myc and Hes1 separately." in: Stem cell research & therapy, Vol. 6, pp. 120, (2015) (PubMed).

Gao, Zhang, Wang, Liu, Zheng, Yang, Huang, Ye, Luo, Xiao: "Hes1 is involved in the self-renewal and tumourigenicity of stem-like cancer cells in colon cancer." in: Scientific reports, Vol. 4, pp. 3963, (2014) (PubMed).

Long, Qiu, Liu, Fei, Feng, Wang, Zhong, Yi, Liu, Zhang, Han: "Functional recovery and neuronal regeneration of a rat model of epilepsy by transplantation of Hes1-down regulated bone marrow stromal cells." in: Neuroscience, Vol. 212, pp. 214-24, (2012) (PubMed).
抗原

HES1 (Hes Family bHLH Transcription Factor 1 (HES1))

别名

HES1 (HES1 产品)

别名

HES-1 antibody, HHL antibody, HRY antibody, bHLHb39 antibody, Hry antibody, HAIRY1 antibody, c-hairy1A antibody, Xhairy1 antibody, hairy1 antibody, hes1 antibody, Xhairy-1 antibody, Xlh1 antibody, hes family bHLH transcription factor 1 antibody, hairy and enhancer of split 1 (Drosophila) antibody, hes family bHLH transcription factor 4 antibody, hes family bHLH transcription factor 1 S homeolog antibody, hes family bHLH transcription factor 1 L homeolog antibody, HES1 antibody, Hes1 antibody, HES4 antibody, hes1.S antibody, hes1.L antibody

背景

Synonyms: HHL, HRY, HES-1, bHLHb39, Transcription factor HES-1, Class B basic helix-loop-helix protein 39, Hairy and enhancer of split 1, Hairy homolog, Hairy-like protein, HES1, HL
Background: Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1. Binds DNA on N-box motifs: 5'-CACNAG-3' with high affinity and on E-box motifs: 5'-CANNTG-3' with low affinity (By similarity). May play a role in a functional FA core complex response to DNA cross-link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage.

基因ID

3280

UniProt

Q14469

途径

DNA Damage Repair