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EXOSC5 抗体 (AA 141-235) (Alexa Fluor 750)

EXOSC5 适用: 小鼠 IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 750
产品编号 ABIN6943382
发货至: 中国
  • 抗原 See all EXOSC5 抗体
    EXOSC5 (Exosome Component 5 (EXOSC5))
    抗原表位
    • 14
    • 9
    • 2
    • 1
    • 1
    • 1
    AA 141-235
    适用
    • 17
    • 17
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    小鼠
    宿主
    • 26
    • 5
    克隆类型
    • 28
    • 3
    多克隆
    标记
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EXOSC5 antibody is conjugated to Alexa Fluor 750
    应用范围
    • 12
    • 12
    • 12
    • 11
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠
    预测反应
    Human,Rat,Dog,Cow,Sheep,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human EXOSC5
    亚型
    IgG
    Top Product
    Discover our top product EXOSC5 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    EXOSC5 (Exosome Component 5 (EXOSC5))
    别名
    EXOSC5 (EXOSC5 产品)
    别名
    si:ch211-194n6.2 antibody, zgc:153707 antibody, EXOSC5 antibody, RRP41B antibody, RRP46 antibody, Rrp46p antibody, hRrp46p antibody, p12B antibody, D7Wsu180e antibody, exosome component 5 antibody, exosc5 antibody, EXOSC5 antibody, Exosc5 antibody
    背景

    Synonyms: Chronic myelogenous leukemia tumor antigen 28, CML28, EXOS5_HUMAN, EXOSC 5, Exosc5, Exosome complex component rrp46, exosome complex exonuclease RRP46, Exosome component 5, exosome component Rrp46, hRrp46p, p12B, Ribosomal RNA processing protein 46, Ribosomal RNA processing protein 46, S. cerevisiae, homolog of, Ribosomal RNA-processing protein 46, RRP41B, RRP46, Rrp46p.

    Background: The exosome is a multisubunit complex composed of several highly conserved subunits, some of which are 3 to 5 exoribonucleases. The complex is involved in a variety of cellular processes and is responsible for degrading unstable mRNAs that contain AU-rich (ARE) elements in their untranslated 3 region. EXOSC5 (Exosome component 5), also known as Exosome complex exonuclease RRP46 and CML28 (Chronic myelogenous leukemia tumor antigen 28), is one of at least eleven components of the exosome complex and is required for processing of 7S pre-RNA to mature 5.8S rRNA. Located in the nucleus, EXOSC5 interacts with both EXOSC1 and EXOSC7. EXOSC5 is exclusively expressed in normal testis, though is found to be highly expressed in many hematopoietic and epithelial tumor cell lines, suggesting that it may be an appropriate target for antigen-specific immunotherapy.

    基因ID
    56915
    UniProt
    Q9NQT4
    途径
    SARS-CoV-2 Protein Interactome
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