CDC34 抗体
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- 抗原 See all CDC34 抗体
- CDC34 (Cell Division Cycle 34 (CDC34))
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This CDC34 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A.
- 免疫原
- Full length protein
- 克隆位点
- 3C2
- 亚型
- IgG
- Top Product
- Discover our top product CDC34 Primary Antibody
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anti-Cell Division Cycle 34 (CDC34) (Internal Region) antibody
CDC34 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) antibodyCDC34 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal CPTC-CDC34-2 unconjugated
anti-Cell Division Cycle 34 (CDC34) antibodyCDC34 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) (AA 1-236) antibodyCDC34 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) antibodyCDC34 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) antibodyCDC34 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) (AA 1-236) antibodyCDC34 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) antibodyCDC34 适用: 人, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) (C-Term) antibodyCDC34 适用: 人, 猴, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 34 (CDC34) antibodyCDC34 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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- 应用备注
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C for 12 months.
- 有效期
- 12 months
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- 抗原
- CDC34 (Cell Division Cycle 34 (CDC34))
- 别名
- Cdc34 (CDC34 产品)
- 别名
- E2-CDC34 antibody, UBC3 antibody, UBCH3 antibody, UBE2R1 antibody, AI327276 antibody, e2-cdc34 antibody, ubc3 antibody, ube2r1 antibody, CDC34 antibody, DNA6 antibody, Ube2r2 antibody, zgc:55452 antibody, fb34h09 antibody, wu:fb34h09 antibody, wu:fe17e09 antibody, zgc:91847 antibody, cell division cycle 34 antibody, cell division cycle 34 L homeolog antibody, SCF E2 ubiquitin-protein ligase catalytic subunit CDC34 antibody, SCF E2 ubiquitin-protein ligase catalytic subunit antibody, cell division cycle 34 homolog (S. cerevisiae) a antibody, cell division cycle 34 homolog (S. cerevisiae) b antibody, CDC34 antibody, Cdc34 antibody, cdc34.L antibody, cdc34 antibody, cdc34a antibody, cdc34b antibody
- 背景
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Synonyms: Ubiquitin-conjugating enzyme E2 R1, (E3-independent) E2 ubiquitin-conjugating enzyme R1, E2 ubiquitin-conjugating enzyme R1, Ubiquitin-conjugating enzyme E2-32 kDa complementing, Ubiquitin-conjugating enzyme E2-CDC34, Ubiquitin-protein ligase R1, CDC34
Background: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-linked polyubiquitination (PubMed:22496338). Cooperates with the E2 UBCH5C and the SCF(FBXW11) E3 ligase complex for the polyubiquitination of NFKBIA leading to its subsequent proteasomal degradation. Performs ubiquitin chain elongation building ubiquitin chains from the UBE2D3-primed NFKBIA-linked ubiquitin. UBE2D3 acts as an initiator E2, priming the phosphorylated NFKBIA target at positions 'Lys-21' and/or 'Lys-22' with a monoubiquitin. Cooperates with the SCF(SKP2) E3 ligase complex to regulate cell proliferation through ubiquitination and degradation of MYBL2 and KIP1. Involved in ubiquitin conjugation and degradation of CREM isoform ICERIIgamma and ATF15 resulting in abrogation of ICERIIgamma- and ATF5-mediated repression of cAMP-induced transcription during both meiotic and mitotic cell cycles. Involved in the regulation of the cell cycle G2/M phase through its targeting of the WEE1 kinase for ubiquitination and degradation. Also involved in the degradation of beta-catenin. Is target of human herpes virus 1 protein ICP0, leading to ICP0-dependent dynamic interaction with proteasomes (PubMed:10329681, PubMed:10373550, PubMed:10871850, PubMed:11675391, PubMed:12037680, PubMed:15652359, PubMed:17461777, PubMed:17698585, PubMed:19112177, PubMed:19126550, PubMed:19945379, PubMed:20061386, PubMed:20347421).
- 基因ID
- 997
- UniProt
- P49427
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