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TP53BP2 抗体

TP53BP2 适用: 人 WB, IHC, IHC (p), IF (cc) 宿主: 兔 Monoclonal 2C3 unconjugated
产品编号 ABIN6942152
发货至: 中国
  • 抗原 See all TP53BP2 抗体
    TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))
    适用
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    宿主
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    • 2
    克隆类型
    • 46
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    单克隆
    标记
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    This TP53BP2 antibody is un-conjugated
    应用范围
    • 46
    • 23
    • 7
    • 5
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    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    交叉反应
    纯化方法
    Purified by Protein A.
    免疫原
    Human ASPP2 aa 1-150
    克隆位点
    2C3
    亚型
    IgG
    Top Product
    Discover our top product TP53BP2 Primary Antibody
  • 应用备注
    WB 1:300-5000
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))
    别名
    ASPP2 (TP53BP2 产品)
    别名
    53BP2 antibody, ASPP2 antibody, BBP antibody, P53BP2 antibody, PPP1R13A antibody, TP53BP2 antibody, AI746547 antibody, Tp53bp2 antibody, X98550 antibody, Trp53bp2 antibody, wu:fa09h08 antibody, wu:fb04e08 antibody, zgc:85720 antibody, tumor protein p53 binding protein 2 antibody, tumor protein p53 binding protein 2 L homeolog antibody, tumor protein p53 binding protein, 2b antibody, transformation related protein 53 binding protein 2 antibody, tumor protein p53 binding protein, 2 antibody, tumor protein p53 binding protein, 2a antibody, TP53BP2 antibody, tp53bp2.L antibody, tp53bp2 antibody, tp53bp2b antibody, Trp53bp2 antibody, Tp53bp2 antibody, tp53bp2a antibody
    背景

    Synonyms: Apoptosis-stimulating of p53 protein 2, Bcl2-binding protein, Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, p53-binding protein 2, p53BP2, TP53BP2, Bbp, 53BP2, p53BP2

    Background: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

    基因ID
    7159
    UniProt
    Q13625
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