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- 抗原 See all SERPINB3 抗体
- SERPINB3 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SERPINB3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant human full-length SERPINB3 protein
- 克隆位点
- CPTC-SERPINB3-2
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product SERPINB3 Primary Antibody
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anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) (AA 276-390) antibody
SERPINB3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) antibodySERPINB3 适用: 人, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3C2 unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) (AA 1-210) antibodySERPINB3 适用: 人 WB, ELISA, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) (AA 1-230) antibodySERPINB3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) antibodySERPINB3 适用: 人 IHC 宿主: 兔 Monoclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) (AA 1-210) antibodySERPINB3 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) (AA 2-383) antibodySERPINB3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) (AA 1-390) antibodySERPINB3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) (AA 1-390) antibodySERPINB3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3) (C-Term) antibodySERPINB3 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: U-2197, HaCaT, Squamous cells. Expressed in some hepatocellular carcinoma.
Known Application: Western Blot (0.5-1.0 μg/mL), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- SERPINB3 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 3 (SERPINB3))
- 别名
- SERPINB3 (SERPINB3 产品)
- 别名
- HsT1196 antibody, SCC antibody, SCCA-1 antibody, SCCA-PD antibody, SCCA1 antibody, T4-A antibody, LEUPIN antibody, PI11 antibody, SCCA-2 antibody, SCCA2 antibody, serpin family B member 3 antibody, serpin family B member 4 antibody, serpin B3 antibody, Somatic cell count antibody, SERPINB3 antibody, SERPINB4 antibody, Serpinb3 antibody, LOC483954 antibody, SCC antibody
- 背景
- Metastasis of a primary tumor to a distant site is determined through signaling cascades that break down interactions between the cell and extracellular matrix proteins. Among the proteins mediating metastasis are serine proteases, such as neutrophil elastase. Serpins are family of serine protease inhibitors, contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. Serine proteases bind to this substrate mimic in a 1:1 stoichiometric fashion and become catalytically inactive. Aberrant expression of serpin family members can contribute to a number of conditions, including emphysema (-1 antitrypsin deficiency), fatal bleeding (elastase to Thrombin specificity) and thrombosis (antithrombin deficiency), and are indicators of cancer stage phenotypes (circulating levels of squamous cell carcinoma antigen, known as SCCA1, increase in advancing stages of some cervical, lung, esophageal and head and neck cancers). SCCA1 expression has been demonstrated to promote oncogenic transformation and epithelial-mesenchymal transition (EMT) in mammary epithelial cells, and its silencing in breast cancer cells has been shown to halt their proliferation.
- 分子量
- 39kDa
- 基因ID
- 6317
- UniProt
- P29508
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