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PTGS2 抗体 (AA 442-572)

PTGS2 适用: 人 WB, ELISA, Coat 宿主: 小鼠 Monoclonal COX2-1941 unconjugated
产品编号 ABIN6940431
发货至: 中国
  • 抗原 See all PTGS2 抗体
    PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))
    抗原表位
    • 16
    • 15
    • 11
    • 7
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    • 6
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    • 4
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    • 3
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    • 1
    • 1
    • 1
    • 1
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    AA 442-572
    适用
    • 101
    • 57
    • 44
    • 21
    • 5
    • 2
    • 2
    • 1
    • 1
    宿主
    • 93
    • 18
    • 2
    小鼠
    克隆类型
    • 89
    • 24
    单克隆
    标记
    • 62
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    This PTGS2 antibody is un-conjugated
    应用范围
    • 99
    • 40
    • 36
    • 29
    • 27
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    • 14
    • 13
    • 8
    • 3
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    • 1
    Western Blotting (WB), ELISA, Coating (Coat)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human COX2 protein fragment (around aa 442-572) (exact sequence is proprietary)
    克隆位点
    COX2-1941
    亚型
    IgG2b kappa
    Top Product
    Discover our top product PTGS2 Primary Antibody
  • 应用备注

    Positive Control: Colon or Lung Carcinoma. HepG2 cells.

    Known Application: ELISA (Use Ab at 2-4 μg/mL for coating) (Order Ab without BSA), Western Blot (0.5-1 μg/mL)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    PTGS2 (Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2))
    别名
    PTGS2 (PTGS2 产品)
    别名
    COX-2 antibody, COX2 antibody, GRIPGHS antibody, PGG/HS antibody, PGHS-2 antibody, PHS-2 antibody, hCox-2 antibody, Cox-2 antibody, Pghs2 antibody, TIS10 antibody, Cox2 antibody, cox-2 antibody, CEF147 antibody, PGHS2 antibody, PHSII antibody, cox2 antibody, gripghs antibody, pgg/hs antibody, pghs-2 antibody, phs-2 antibody, PTGS2 antibody, hcox-2 antibody, fj02a10 antibody, ptgs2 antibody, unp1239 antibody, wu:fj02a10 antibody, zCOX-2 antibody, si:dkey-97o5.6 antibody, prostaglandin-endoperoxide synthase 2 antibody, prostaglandin G/H synthase 2 antibody, prostaglandin-endoperoxide synthase 2S homeolog antibody, prostaglandin-endoperoxide synthase 2a antibody, prostaglandin-endoperoxide synthase 2b antibody, PTGS2 antibody, Ptgs2 antibody, LOC100136456 antibody, ptgs2.S antibody, ptgs2 antibody, ptgs2a antibody, ptgs2b antibody
    背景
    Prostaglandins are a diverse group of autocrine and paracrine hormones that mediate many cellular and physiologic processes. Prostaglandin H2 (PGH2) is an intermediate molecule in formation of the prostaglandins. Cyclooxygenase-1 (Cox-1) and cyclooxygenase-2 (Cox-2) are prostaglandin synthases that catalyze the formation of PGH2 from arachidonic acid (AA). Cox-1 and Cox-2 are isozymes of prostaglandin-endoperoxidase synthase (PTGS). Cox-1 is constitutively expressed in most tissues and is thought to serve in general housekeeping functions. Cox-2 is efficiently induced in migratory cells responding to pro-inflammatory stimuli and is considered to be an important mediator of inflammation. Both enzymes are targets for the nonsteroidal therapeutic anti-inflammatory drugs, NSAIDs. COX2 expression is significantly increased in 85-90 % of human colorectal adenocarcinomas whereas levels of COX-1 are not changed.
    分子量
    70-72kDa
    基因ID
    5743
    UniProt
    P35354
    途径
    Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
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