CD51 抗体
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北京 101111
Quick Overview for CD51 抗体 (ABIN6939816)
抗原
See all CD51 (ITGAV) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- CD51 / Integrin V Antibody
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特异性
- Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
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纯化方法
- 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.
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免疫原
- Recombinant human full-length integrin alpha V beta 1 protein
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亚型
- IgG1, kappa
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应用备注
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Positive Control: Squamous cells, A375M melanoma cells. A549 cells.
Known Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- CD51 (ITGAV) (Integrin alpha V (ITGAV))
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别名
- ITGAV
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背景
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antigen identified by monoclonal antibody L230, CD 51, CD51, DKFZp686A08142, Integrin alpha five, integrin alpha V beta 3, Integrin alpha-5, integrin alpha-V, Integrin alpha-V light chain, integrin alphaVbeta3, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), ITAV_HUMAN, ITGAV, MSK 8, Msk8, Vitronectin receptor subunit alpha, VNRA, VTNR
A375M melanoma cells. A549 cells., Squamous cells
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分子量
- 150-160kDa under non-reducing conditions. Under reducing conditions|it is cleaved into 2 bands of about 125-130kDa +20-25kDa.
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基因ID
- 3685, 436873
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UniProt
- P06756
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途径
- Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
抗原
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