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CD51 抗体

The 小鼠 单克隆 anti-CD51 antibody is suitable to detect CD51 in samples from 人. It has been validated for WB, FACS, ELISA 和 IF.
产品编号 ABIN6939816
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD51 抗体 (ABIN6939816)

抗原

See all CD51 (ITGAV) 抗体
CD51 (ITGAV) (Integrin alpha V (ITGAV))

适用

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小鼠

克隆类型

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单克隆

标记

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This CD51 antibody is un-conjugated

应用范围

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Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunofluorescence (IF)

克隆位点

ITGAV-1610
  • 原理

    CD51 / Integrin V Antibody

    特异性

    Integrins are heterodimers composed of noncovalently associated transmembrane both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

    纯化方法

    200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G.

    免疫原

    Recombinant human full-length integrin alpha V beta 1 protein

    亚型

    IgG1, kappa
  • 应用备注

    Positive Control: Squamous cells, A375M melanoma cells. A549 cells.

    Known Application: ELISA (For coating use Ab at 1-5 μg/mL, order Ab without BSA), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    CD51 (ITGAV) (Integrin alpha V (ITGAV))

    别名

    ITGAV

    背景

    antigen identified by monoclonal antibody L230, CD 51, CD51, DKFZp686A08142, Integrin alpha five, integrin alpha V beta 3, Integrin alpha-5, integrin alpha-V, Integrin alpha-V light chain, integrin alphaVbeta3, integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51), ITAV_HUMAN, ITGAV, MSK 8, Msk8, Vitronectin receptor subunit alpha, VNRA, VTNR

    A375M melanoma cells. A549 cells., Squamous cells

    分子量

    150-160kDa under non-reducing conditions. Under reducing conditions|it is cleaved into 2 bands of about 125-130kDa +20-25kDa.

    基因ID

    3685, 436873

    UniProt

    P06756

    途径

    Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex
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