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IGF1 抗体

IGF1 适用: 人, 小鼠, 大鼠, 兔 IHC, ELISA, IF, FACS, Neut, AcA, in vitro, Coat 宿主: 小鼠 Monoclonal SPM406 unconjugated
产品编号 ABIN6939700
发货至: 中国
  • 抗原 See all IGF1 抗体
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    适用
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    人, 小鼠, 大鼠, 兔
    宿主
    • 123
    • 49
    • 9
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    • 1
    • 1
    小鼠
    克隆类型
    • 133
    • 51
    单克隆
    标记
    • 91
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    This IGF1 antibody is un-conjugated
    应用范围
    • 143
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    Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Neutralization (Neut), Activity Assay (AcA), In vitro Assay (in vitro), Coating (Coat)
    特异性
    This antibody is specific to Insulin-like Growth Factor (IGF-1) and shows minimal cross-reaction with IGF-11, Proinsulin, MSF, and Insulin. IGF-1 is a polypeptide growth factor with two isoforms that are produced by alternative splicing. Isoform 1 is also known as IGF-IB while isoform 2 is known as IGF-IA. IGF-1 stimulates the proliferation of a wide range of cell types including muscle, bone and cartilage tissue. It functions as an autocrine regulator of growth. Activation of IGF system has emerged as a key factor for tumor progression and resistance to apoptosis in many cancers like those of breast, thyroid and colon.
    纯化方法
    Purified by Protein A/G
    免疫原
    Purified human IGF-1 protein
    克隆位点
    SPM406
    亚型
    IgG1 kappa
    Top Product
    Discover our top product IGF1 Primary Antibody
  • 应用备注

    Positive Control: Pancreas or brain. Breast, Thyroid or Colon Cancers, IGF-1 recombinant protein.

    Known Application: ELISA (For coating, purchase antibody without BSA), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT), In-vitro Neutralization of Biological Activity of IGF-1 (Order Ab without Azide)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    IGF1 (Insulin-Like Growth Factor 1 (IGF1))
    别名
    IGF1 (IGF1 产品)
    分子量
    ~7.6kDa
    基因ID
    3479
    UniProt
    P05019
    途径
    RTK signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Peptide Hormone Metabolism, Hormone Activity, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Stem Cell Maintenance, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Smooth Muscle Cell Migration, Activated T Cell Proliferation, Positive Regulation of fat Cell Differentiation
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