HLA-DRB3 抗体
Quick Overview for HLA-DRB3 抗体 (ABIN6939646)
抗原
See all HLA-DRB3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This MAb reacts with the HLA-DRB3 antigen, a member of MHC class II molecules.It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
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纯化方法
- Purified by Protein A/G
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免疫原
- Human REH cells (non-T, non-B leukemia cell line)
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亚型
- IgG2a kappa
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anti-Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3) (AA 1-266) antibody
HLA-DRB3 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3) (AA 111-227) antibodyHLA-DRB3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3) (AA 1-266) antibodyHLA-DRB3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3) antibodyHLA-DRB3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3) antibodyHLA-DRB3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3) (AA 150-199) antibodyHLA-DRB3 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3) (AA 30-227) antibodyHLA-DRB3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3) antibodyHLA-DRB3 适用: 人 IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Positive Control: Ramos, Daudi or HuT78 cells. Tonsil or lymph node.
Known Application: Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.
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限制
- 仅限研究用
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浓度
- 200 μg/mL
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缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-80 °C
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储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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有效期
- 24 months
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- HLA-DRB3 (Major Histocompatibility Complex, Class II, DR beta 3 (HLA-DRB3))
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别名
- HLA-DRB3
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分子量
- ~28kDa (beta chain)
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基因ID
- 3123
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UniProt
- P01911
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途径
- TCR Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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