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- 抗原 See all HLA-B 抗体
- HLA-B (Major Histocompatibility Complex, Class I, B (HLA-B))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HLA-B antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Normal human peripheral blood lymphocytes
- 克隆位点
- JOAN-1
- 亚型
- IgG3 kappa
- Top Product
- Discover our top product HLA-B Primary Antibody
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anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 26-309) antibody
HLA-B 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 241-362) antibodyHLA-B 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 2A11G7 unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 75-107), (N-Term) antibodyHLA-B 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB47637 unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 1-100) antibodyHLA-B 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) antibodyHLA-B 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 25-308) antibodyHLA-B 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 1-362) antibodyHLA-B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 209-295) antibodyHLA-B 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4D4B6 unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 243-308) antibodyHLA-B 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, B (HLA-B) (AA 197-306) antibodyHLA-B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: Human peripheral blood lymphocytes, tonsil or lymph node.
Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- HLA-B (Major Histocompatibility Complex, Class I, B (HLA-B))
- 别名
- HLA-B (HLA-B 产品)
- 别名
- AS antibody, HLAB antibody, SPDA1 antibody, mhc1b antibody, major histocompatibility complex, class I, B antibody, major histocompatibility complex nonclassical class Ib L homeolog antibody, HLA-B antibody, BOLA-B antibody, MAMU-B18 antibody, DKFZP469N1225 antibody, mhc1b.L antibody
- 背景
- HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described.
- 分子量
- 45kDa
- 基因ID
- 3106
- UniProt
- P01889
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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