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HLA-ABC 抗体

This anti-HLA-ABC antibody is a 小鼠 单克隆 antibody detecting HLA-ABC in FACS 和 IF. Suitable for 人, 小鼠 和 Non-Human Primate.
产品编号 ABIN6939617
发货至: 中国

Quick Overview for HLA-ABC 抗体 (ABIN6939617)

抗原

See all HLA-ABC 抗体
HLA-ABC

适用

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人, 小鼠, Non-Human Primate

宿主

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小鼠

克隆类型

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单克隆

标记

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This HLA-ABC antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

246-B8-E7
  • 特异性

    Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.

    纯化方法

    Purified by Protein A/G

    免疫原

    Human peripheral blood leukocytes

    亚型

    IgG2a kappa
  • 应用备注

    Positive Control: THP-1 and Jurkat cells. Tonsil or lymph node.

    Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    HLA-ABC

    别名

    HLA-A, HLA-B, HLA-C

    分子量

    ~41kDa

    基因ID

    3105, 3106, 3107

    UniProt

    P01889, P30443, P30499

    途径

    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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