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Neuregulin 1 抗体 (AA 21-242)

This anti-Neuregulin 1 antibody is a 小鼠 单克隆 antibody detecting Neuregulin 1 in IHC 和 StM. Suitable for 人.
产品编号 ABIN6939613
发货至: 中国

Quick Overview for Neuregulin 1 抗体 (AA 21-242) (ABIN6939613)

抗原

See all Neuregulin 1 (NRG1) 抗体
Neuregulin 1 (NRG1)

适用

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宿主

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小鼠

克隆类型

  • 128
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单克隆

标记

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This Neuregulin 1 antibody is un-conjugated

应用范围

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Immunohistochemistry (IHC), Staining Methods (StM)

克隆位点

NRG1-2710
  • 抗原表位

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    AA 21-242

    纯化方法

    Purified by Protein A/G

    免疫原

    Recombinant fragment of human Neuregulin-1 (NRG1) protein (around aa 21-242) (exact sequence is proprietary)

    亚型

    IgG1 kappa
  • 应用备注

    Positive Control: A431, MCF-7 or T47D cells. Breast, Bladder or Thyroid Carcinoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制

    仅限研究用
  • 浓度

    200 μg/mL

    缓冲液

    10 mM PBS with 0.05 % BSA & 0.05 % azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-80 °C

    储存方法

    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

    有效期

    24 months
  • 抗原

    Neuregulin 1 (NRG1)

    别名

    NRG1

    背景

    Heregulin-1 is a membrane glycoprotein that mediates cell-cell signaling and plays a critical role in the growth and development of multiple organ systems. An extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are expressed in a tissue-specific manner and differ significantly in their structure, and are classified as types I, II, III, IV, V and VI. Dysregulation of this gene has been linked to diseases such as cancer, schizophrenia, and bipolar disorder (BPD).

    分子量

    26-71kDa

    基因ID

    3084

    UniProt

    Q02297

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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