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- 抗原 See all FCGR2A 抗体
- FCGR2A (Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FCGR2A antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Functional Studies (Func)
- 特异性
- This MAb reacts with a CD32 (FcgRII) epitope (cluster-4). It displays a stronger reaction with Daudi than with U937 cells. The epitope is located in domain 2 of FcgRIIa. Its Fab'2 fragments block immune complex binding. CD32 (FcRII) is a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i.e., IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- K562 and FcgRII+L cells
- 克隆位点
- 7-3
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product FCGR2A Primary Antibody
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anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) antibody
FCGR2A 适用: 人 WB, IF, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 9C6 unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) antibodyFCGR2A 适用: 人, 猴 WB, IHC, IP, IHC (p) 宿主: 小鼠 Monoclonal 20D1 unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (AA 241-317) antibodyFCGR2A 适用: 人 WB, ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (C-Term) antibodyFCGR2A 适用: 人 WB, ELISA, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) antibodyFCGR2A 适用: 人 WB, IF, IHC, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal 6H7 unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (AA 34-316) antibodyFCGR2A 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (AA 46-150) antibodyFCGR2A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E8 unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (AA 1-316) antibodyFCGR2A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (C-Term) antibodyFCGR2A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) antibodyFCGR2A 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 3B6 unconjugated Recombinant Antibody
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- 应用备注
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Positive Control: K-562 cells. Lymph node, tonsil and placenta.
Known Application: Functional Studies (Order Ab without BSA & Azide)Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- FCGR2A (Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A))
- 别名
- FCGR2A (FCGR2A 产品)
- 别名
- CD32 antibody, CD32A antibody, CDw32 antibody, FCG2 antibody, FCGR2 antibody, FCGR2A1 antibody, FcGR antibody, IGFR2 antibody, CD32a antibody, Fc fragment of IgG receptor IIa antibody, FCGR2A antibody
- 分子量
- 40kDa
- 基因ID
- 2212
- UniProt
- P12318
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