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FCGR2A 抗体

FCGR2A 适用: 人 IF, FACS, Func 宿主: 小鼠 Monoclonal FCGR2A-479 unconjugated
产品编号 ABIN6939374
发货至: 中国
  • 抗原 See all FCGR2A 抗体
    FCGR2A (Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A))
    适用
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    宿主
    • 43
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    小鼠
    克隆类型
    • 41
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    单克隆
    标记
    • 33
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    This FCGR2A antibody is un-conjugated
    应用范围
    • 37
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    Immunofluorescence (IF), Flow Cytometry (FACS), Functional Studies (Func)
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human FCGR2A protein
    克隆位点
    FCGR2A-479
    亚型
    IgG2b kappa
    Top Product
    Discover our top product FCGR2A Primary Antibody
  • 应用备注

    Positive Control: K-562 cells. Lymph node, tonsil and placenta.

    Known Application: Functional Studies (Order Ab without BSA & Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    FCGR2A (Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A))
    别名
    FCGR2A (FCGR2A 产品)
    别名
    CD32 antibody, CD32A antibody, CDw32 antibody, FCG2 antibody, FCGR2 antibody, FCGR2A1 antibody, FcGR antibody, IGFR2 antibody, CD32a antibody, Fc fragment of IgG receptor IIa antibody, FCGR2A antibody
    背景
    This MAb binds most strongly to the IIa isoforms of CD32 (FcRII), a type 1 transmembrane glycoprotein that mediates several functions including phagocytosis, cytotoxicity, and immunomodulation as well as platelet aggregation. Three genes (A, B, and C) encode CD32 and at least 6 isoforms are generated via alternative mRNA splicing, i.e., IIa1, IIa2, IIb1, IIb2, IIb3 and IIc. Monocytes/macrophages, placental trophoblasts and endothelial cells express all isoforms. In addition, the IIb isoform is expressed by B cells, and the IIa isoform by platelets, granulocytes and, weakly, by B cells. NK cells and neutrophils express Isoform IIc. CD32 binds weakly to the Fc region of monomeric IgG but more strongly to IgG aggregates and immune complexes.
    分子量
    40kDa
    基因ID
    2212
    UniProt
    P12318
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