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SERPINA3 抗体 (AA 49-187)

SERPINA3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal AACT-1451 unconjugated
产品编号 ABIN6939169
发货至: 中国
  • 抗原 See all SERPINA3 抗体
    SERPINA3 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))
    抗原表位
    • 15
    • 12
    • 9
    • 5
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    • 1
    • 1
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    • 1
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    • 1
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    AA 49-187
    适用
    • 73
    • 18
    • 17
    • 1
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    宿主
    • 57
    • 27
    • 3
    • 2
    小鼠
    克隆类型
    • 56
    • 33
    单克隆
    标记
    • 48
    • 6
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    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
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    • 1
    • 1
    • 1
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    • 1
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    This SERPINA3 antibody is un-conjugated
    应用范围
    • 55
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    • 8
    • 5
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    Immunohistochemistry (IHC), Staining Methods (StM)
    特异性
    It recognizes a protein of 65-76 kDa, which is identified antichymotrypsin (AACT). AACT is a plasma protease inhibitor synthesized in the liver as a single glycopeptide chain. In human, the normal serum level of AACT is about one-tenth that of their concentrations in plasma increase in response to trauma, surgery and infection. Elevated levels of AACT are widely, but not universally, reported in the cerebrospinal fluid and plasma of AD patients. Prostate-specific antigen (PSA) and its SDS-stable complex with AACT are in widespread use as markers for the diagnosis of prostate cancer. AACT deficiency may also be a possible cause of chronic liver disease. AACT antibody reacts with histiocytes and histiocytic neoplasms. It is widely used to identify histiocytes and tumors derived from them. Acinar tumors of the pancreas and salivary gland may also exhibit AACT positivity.
    纯化方法
    Purified by Protein A/G
    免疫原
    Recombinant human Antichymotrypsin (AACT) protein fragment (around aa 49-187) (exact sequence is proprietary)
    克隆位点
    AACT-1451
    亚型
    IgG1 kappa
    Top Product
    Discover our top product SERPINA3 Primary Antibody
  • 应用备注

    Positive Control: HeLa cells. Tonsil, Pancreas or Histiocytoma.

    Known Application: Immunohistochemistry (Formalin-fixed) (0.5-1 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    SERPINA3 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))
    别名
    SERPINA3 (SERPINA3 产品)
    别名
    SERPINA3-1 antibody, Pi2 antibody, AACT antibody, ACT antibody, GIG25 antibody, A1AT antibody, PI antibody, alpha-1-PI antibody, AAT antibody, Pi antibody, Spi1 antibody, SERPINA3-5 antibody, serpina3 antibody, serpin A3-5 antibody, serpin family A member 3 antibody, alpha-1-antiproteinase F precursor antibody, serpin family A member 1 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 L homeolog antibody, LOC396684 antibody, SERPINA3 antibody, LOC100008973 antibody, SERPINA1 antibody, Serpina1 antibody, SPIA5 antibody, serpina3.L antibody
    分子量
    65-76kDa
    基因ID
    12
    UniProt
    P01011
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