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- 抗原 See all CGA 抗体
- CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CGA antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM), Immunostaining (ISt)
- 特异性
- This MAb reacts with a protein of ~13 kDa, identified as alpha sub-unit of Luteinizing Hormone (LH). Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor, however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant full-length hLH alpha protein
- 克隆位点
- LHa-756
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product CGA Primary Antibody
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anti-Glycoprotein Hormones, alpha Polypeptide (CGA) (AA 25-147) antibody
CGA 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E6B3 unconjugated
anti-Glycoprotein Hormones, alpha Polypeptide (CGA) (AA 25-120) antibodyCGA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Hormones, alpha Polypeptide (CGA) (AA 1-100) antibodyCGA 适用: Synthetic IHC (f) 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
anti-Glycoprotein Hormones, alpha Polypeptide (CGA) antibodyCGA 适用: 人 IHC, StM, ISt 宿主: 小鼠 Monoclonal HCGa-53 unconjugated
anti-Glycoprotein Hormones, alpha Polypeptide (CGA) (Internal Region) antibodyCGA 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Hormones, alpha Polypeptide (CGA) (AA 25-116) antibodyCGA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Hormones, alpha Polypeptide (CGA) (AA 25-116) antibodyCGA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Hormones, alpha Polypeptide (CGA) antibodyCGA 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Hormones, alpha Polypeptide (CGA) antibodyCGA 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Glycoprotein Hormones, alpha Polypeptide (CGA) (AA 1-116) antibodyCGA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: Anterior Pituitary.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(No special pre-treatment is required for staining of formalin-fixed tissues. Note that HIER is NOT recommended for this antibody.)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))
- 别名
- LHA (CGA 产品)
- 别名
- CG-ALPHA antibody, FSHA antibody, GPHA1 antibody, GPHa antibody, HCG antibody, LHA antibody, TSHA antibody, CG-alpha antibody, GPHalpha antibody, Tsha antibody, aGSU antibody, alpha-GSU antibody, alphaGSU antibody, alphaSU antibody, CGA antibody, FSH-alpha antibody, LSH-alpha antibody, TSH-alpha antibody, cg-alpha antibody, cga antibody, cga-a antibody, cga-b antibody, fsha antibody, gpha antibody, gpha1 antibody, hcg antibody, lha antibody, tsha antibody, GTH-alpha antibody, gsu-alpha antibody, glycoprotein hormones, alpha polypeptide antibody, glycoprotein hormones, alpha subunit antibody, chromogranin A antibody, glycoprotein hormones, alpha polypeptide L homeolog antibody, CGA antibody, Cga antibody, CHGA antibody, cga.L antibody, cga antibody
- 分子量
- ~13kDa
- 基因ID
- 1081
- UniProt
- P01215
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport, Peptide Hormone Metabolism
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