SERPINA3 抗体 (AA 49-187)
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- 抗原 See all SERPINA3 抗体
- SERPINA3 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))
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抗原表位
- AA 49-187
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SERPINA3 antibody is un-conjugated
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应用范围
- Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- It recognizes a protein of 65-76 kDa, which is identified antichymotrypsin (AACT). AACT is a plasma protease inhibitor synthesized in the liver as a single glycopeptide chain. In human, the normal serum level of AACT is about one-tenth that of i± 1-antitrypsin (AAT), with which it shares nucleic acid and protein sequence homology. Both are major acute phase reactants, their concentrations in plasma increase in response to trauma, surgery and infection. Elevated levels of AACT are widely, but not universally, reported in the cerebrospinal fluid and plasma of AD patients. Prostate-specific antigen (PSA) and its SDS-stable complex with AACT are in widespread use as markers for the diagnosis of prostate cancer. AACT deficiency may also be a possible cause of chronic liver disease. AACT antibody reacts with histiocytes and histiocytic neoplasms. It is widely used to identify histiocytes and tumors derived from them. Acinar tumors of the pancreas and salivary gland may also exhibit AACT positivity.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant human Antichymotrypsin (AACT) protein fragment (around aa 49-187) (exact sequence is proprietary)
- 克隆位点
- AACT-1451
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product SERPINA3 Primary Antibody
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anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) (AA 1-423) antibody
SERPINA3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) (AA 279-432) antibodySERPINA3 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 5G3C11 unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) (AA 25-423) antibodySERPINA3 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1E6 unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) (AA 23-253) antibodySERPINA3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) (AA 25-423) antibodySERPINA3 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1C10 unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) (AA 24-423) antibodySERPINA3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) (AA 235-394) antibodySERPINA3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) antibodySERPINA3 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) (AA 1-423) antibodySERPINA3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) (AA 121-320) antibodySERPINA3 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa cells. Human tonsil, pancreas or histiocytoma.
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- SERPINA3 (serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3))
- 别名
- SERPINA3 (SERPINA3 产品)
- 别名
- SERPINA3-1 antibody, Pi2 antibody, AACT antibody, ACT antibody, GIG25 antibody, A1AT antibody, PI antibody, alpha-1-PI antibody, AAT antibody, Pi antibody, Spi1 antibody, SERPINA3-5 antibody, serpina3 antibody, serpin A3-5 antibody, serpin family A member 3 antibody, alpha-1-antiproteinase F precursor antibody, serpin family A member 1 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 antibody, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 L homeolog antibody, LOC396684 antibody, SERPINA3 antibody, LOC100008973 antibody, SERPINA1 antibody, Serpina1 antibody, SPIA5 antibody, serpina3.L antibody
- 背景
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SERPINA3, AACT, ACT, Cell growth-inhibiting gene 24/25 protein, GIG24, GIG25, Growth inhibiting protein 24, Growth inhibiting protein 25, Serine (or cysteine) proteinase inhibitor clade A member 3, Serpin A3, Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3,Alpha-1-Antichymotrypsin (SERPINA3) (Histiocytoma Marker)
Cellular localisation: Cytoplasm - 分子量
- 65-76kDa
- 基因ID
- 12, 534293, 710488
- UniProt
- P01011
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