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Myogenin 抗体

MYOG 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal MYOG-2660 unconjugated
产品编号 ABIN6938005
发货至: 中国
  • 抗原 See all Myogenin (MYOG) 抗体
    Myogenin (MYOG) (Myogenin (Myogenic Factor 4) (MYOG))
    适用
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    宿主
    • 72
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    小鼠
    克隆类型
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    单克隆
    标记
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    This Myogenin antibody is un-conjugated
    应用范围
    • 102
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    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    Myogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif.MyoD family members share about 80% amino acid homology in their bHLH motifs.Anti-myogenin labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms' tumor.
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant full-length human myogenin (MYOG) protein
    克隆位点
    MYOG-2660
    亚型
    IgG1 kappa
    Top Product
    Discover our top product MYOG Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Rh-30 cells. Skeletal muscle or rhabdomyosarcoma.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    Myogenin (MYOG) (Myogenin (Myogenic Factor 4) (MYOG))
    别名
    MYOG (MYOG 产品)
    别名
    cb553 antibody, zgc:100763 antibody, LOC446037 antibody, myf4 antibody, Xmyog antibody, myogenin antibody, LOC100136471 antibody, LOC100224062 antibody, LOC100303673 antibody, MYF4 antibody, bHLHc3 antibody, myo antibody, myf-4 antibody, myogenin antibody, myogenin (myogenic factor 4) antibody, MYOG antibody, myog antibody, LOC100303673 antibody, Myog antibody
    背景
    BHLHc3, cb553, Class C basic helix-loop-helix protein 3, Myf-4, MYF4, MYOG, Myogenic factor 4,Myogenin / Myf-4 (Skeletal Muscle Marker)
    Cellular localisation: Nuclear
    分子量
    34kDa
    基因ID
    4656, 2830
    UniProt
    P15173
    途径
    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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