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CD103 抗体

ITGAE 适用: 人 IHC (f) 宿主: 小鼠 Monoclonal ITGAE-2063 unconjugated
产品编号 ABIN6937579
发货至: 中国
  • 抗原 See all CD103 (ITGAE) 抗体
    CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CD103 antibody is un-conjugated
    应用范围
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    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    特异性
    This MAb recognizes a protein of 150 kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E beta-7 (aEb7) integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95 % of intraepithelial CD8+ cells and on 40 % of mucosa-associated T cells, whereas less than 2 % of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Antibody to CD103 is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL).
    交叉反应 (详细)
    Human.
    纯化方法
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    免疫原
    Recombinant human ITGAE protein fragment (exact sequence is proprietary)
    克隆位点
    ITGAE-2063
    亚型
    IgG2c kappa
    Top Product
    Discover our top product ITGAE Primary Antibody
  • 应用备注

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: Tonsil, Colon or Stomach.

    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    储存液
    Azide free
    储存条件
    -20 °C,-80 °C
    储存方法
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    有效期
    24 months
  • 抗原
    CD103 (ITGAE) (Integrin, alpha E (Antigen CD103, Human Mucosal Lymphocyte Antigen 1, alpha Polypeptide) (ITGAE))
    别名
    ITGAE (ITGAE 产品)
    别名
    A530055J10 antibody, CD103 antibody, aM290 antibody, alpha-E1 antibody, alpha-M290 antibody, HUMINAE antibody, integrin alpha E, epithelial-associated antibody, integrin subunit alpha E antibody, Itgae antibody, ITGAE antibody
    背景
    CD103, Human mucosal lymphocyte antigen 1 (HML1 antigen), Integrin alpha E heavy chain, Integrin alpha E light chain, Integrin alpha E, epithelial-associated, Integrin alpha E1, Integrin alpha-IEL (intestinal intraepithelial lymphocytes), Integrin alpha M290, Integrin alpha-E heavy chain, Integrin, alpha E (ITGAE),CD103 / Integrin 'E'7 (T-Cell Lymphoma & Hairy Cell Leukemia Marker)
    Cellular localisation: Cell surface and cytoplasm
    分子量
    150kDa
    基因ID
    3682, 513867
    UniProt
    P38570
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