HLA-A 抗体
Quick Overview for HLA-A 抗体 (ABIN6937390)
抗原
See all HLA-A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This MAb reacts with cells bearing HLA-A25 or HLA-Aw32 antigens. In addition, a reaction was observed with a cell of phenotype A2, Aw31, B17, Bw49. HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. HLA system comprises closely linked genes controlling highly polymorphic proteins involved in the presentation of peptides to the T-cell receptor, inhibition of NK cell cytotoxicity, and rejection of tissue allotransplantation. Specific alleles at HLA loci are associated with diseases. This MAb is specifically applicable for typing peripheral T cells for the antigens HLA-A25 and HLA-Aw32.
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交叉反应 （详细）
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Normal human peripheral blood lymphocytes of phenotype A1, Aw32, B7, B37, Cw-, Cw-, DR2, DRw10
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亚型
- IgG2a kappa
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anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 35-285) antibody
HLA-A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) antibodyHLA-A 适用: 人, 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 1-365) antibodyHLA-A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 24-365) antibodyHLA-A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D6 unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 1-365) antibodyHLA-A 适用: 人 FACS, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) antibodyHLA-A 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 70-99) antibodyHLA-A 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) antibodyHLA-A 适用: 人 FACS, IF 宿主: 小鼠 Monoclonal 108-2C5 unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) antibodyHLA-A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 82-106), (N-Term) antibodyHLA-A 适用: 人 WB, IF, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.
Positive_Control: THP-1 and Jurkat cells. Tonsil or lymph node.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- HLA-A (Major Histocompatibility Complex, Class I, A (HLA-A))
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别名
- HLA-A
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背景
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HLA-A, HLA class 1A, MHC class I HLA-A,HLA-Aw32 & HLA-A25 (MHC I)
Cellular localisation: Cell Surface -
分子量
- ~41kDa
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基因ID
- 3105, 181244, 654404
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UniProt
- P01889, P30443, P30499
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途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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