HGF 抗体
Quick Overview for HGF 抗体 (ABIN6937376)
抗原
See all HGF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This gene encodes a protein that binds to the hepatocyte growth factor receptor to regulate cell growth, cell motility and morphogenesis in numerous cell and tissue types. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate alpha and beta chains, which form the mature heterodimer. This protein is secreted by mesenchymal cells and acts as a multi-functional cytokine on cells of mainly epithelial origin. This protein also plays a role in angiogenesis, tumorogenesis, and tissue regeneration. Although the encoded protein is a member of the peptidase S1 family of serine proteases, it lacks peptidase activity. Mutations in this gene are associated with nonsyndromic hearing loss.
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交叉反应 (详细)
- Human.
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纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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免疫原
- Recombinant full-length human HGF/SF protein.
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亚型
- IgG2b kappa
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应用备注
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Known_Application: ELISA (For coating, order antibody without BSA),Optimal dilution for a specific application should be determined.
Positive_Control: HGF lysate.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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储存液
- Azide free
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储存条件
- -20 °C,-80 °C
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储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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有效期
- 24 months
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- HGF (Hepatocyte Growth Factor (Hepapoietin A, Scatter Factor) (HGF))
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别名
- HGF
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背景
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F-TCF, Fibroblast derived tumor cytotoxic factor, Hepatocyte growth factor (hepapoietin A, scatter factor), Hepatocyte growth factor beta chain, Hepatopoietin-A, HGF, HGFB, HPTA, Lung fibroblast derived mitogen, Scatter Factor,HGF / SF
Cellular localisation: Cytoplasmic -
分子量
- 91/64/34kDa precursor//
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基因ID
- 3082, 396530, 561679
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UniProt
- P14210
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途径
- RTK signaling, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
抗原
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